Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.52 |
| ▸ | AURKB | Q96GD4 | 4/20 | 0.52 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.52 |
| ▸ | YES1 | P07947 | 2/20 | 0.52 |
| ▸ | ABL1 | P00519 | 1/20 | 0.52 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | FGFR3 | P22607 | 12/20 | 0.46 |
| ▸ | FGFR2 | P21802 | 10/20 | 0.46 |
| ▸ | FGFR4 | P22455 | 10/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 9/20 | 0.46 |
| ▸ | KDR | P35968 | 7/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 2/20 | 0.41 |
| ▸ | MST1R | Q04912 | 1/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17247735 | 0.90 | MAPK1 (0.48) | MAPK1AURKBNTRK1YES1ABL1 | |
| SCHEMBL17247754 | 0.89 | MAPK1 (0.51) | MAPK1AURKBNTRK1YES1ABL1 | |
| SCHEMBL17247746 | 0.89 | MAPK14 (0.42) | MAPK1AURKBNTRK1YES1ABL1 | |
| SCHEMBL17247601 | 0.89 | FGFR2 (0.43) | MAPK1AURKBNTRK1YES1ABL1 | |
| SCHEMBL17247880 | 0.88 | MAPK1 (0.46) | MAPK1AURKBNTRK1YES1ABL1 | |
| SCHEMBL17239939 | 0.88 | MAPK1 (0.46) | MAPK1AURKBNTRK1YES1ABL1 | |
| SCHEMBL17240068 | 0.87 | MAPK1 (0.53) | MAPK1AURKBNTRK1YES1ABL1 | |
| SCHEMBL15884770 | 0.87 | MET (0.40) | MAPK1AURKBNTRK1YES1ABL1 | |
| SCHEMBL17239931 | 0.87 | MAPK1 (0.39) | MAPK1AURKBNTRK1YES1ABL1 | |
| SCHEMBL17255457 | 0.87 | AURKB (0.43) | MAPK1AURKBNTRK1YES1ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2944637-B1 | NITROGEN-CONTAINING HETEROCYLIC COMPOUND OR SALT THEREOF | FUJIFILM CORP (JP) | 2020-02-19 | — | — | EP | disclosed |
| US-9783536-B2 | Nitrogen-containing heterocyclic compound or salt thereof | FUJIFILM CORPORATION (JP) | 2017-10-10 | — | — | US | disclosed |
| US-9783536-B2 | Nitrogen-containing heterocyclic compound or salt thereof | FUJIFILM CORPORATION (JP) | 2017-10-10 | — | — | US | disclosed |
| EP-2944637-A1 | NITROGEN-CONTAINING HETEROCYLIC COMPOUND OR SALT THEREOF | FUJIFILM Corporation (JP) | 2015-11-18 | — | — | EP | disclosed |