SCHEMBL17248255

SCHEMBL17248255

c1ccc(-c2nc(-n3c4ccccc4c4ccccc43)cc(-n3c4ccccc4c4c3ccc3c5ccccc5n(-c5ccccc5)c34)n2)cc1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
ATM Q13315 1/20 0.41
HTT P42858 2/20 0.38
MAPT P10636 3/20 0.35
TSHR P16473 2/20 0.35
MAPK1 P28482 2/20 0.35
HSD17B10 Q99714 2/20 0.35
LMNA P02545 2/20 0.35
KMT2A Q03164 3/20 0.34
IL1R1 P14778 1/20 0.34
MEN1 O00255 2/20 0.33
NPSR1 Q6W5P4 1/20 0.33
ALDH1A1 P00352 1/20 0.33
ABCG2 Q9UNQ0 1/20 0.33
PTGER4 P35408 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21578509 1.00 KDM4E (0.41) KDM4EL3MBTL1ATMHTTMAPT
SCHEMBL24164201 0.96 KDM4E (0.44) KDM4EL3MBTL1ATMHTTMAPT
SCHEMBL12456623 0.95 KDM4E (0.41) KDM4EL3MBTL1ATMHTTMAPT
SCHEMBL17248304 0.95 KDM4E (0.45) KDM4EL3MBTL1ATMHTTMAPT
SCHEMBL17248256 0.94 MAPT (0.41) KDM4EL3MBTL1ATMHTTMAPT
SCHEMBL21017908 0.93 KDM4E (0.43) KDM4EL3MBTL1ATMHTTMAPT
SCHEMBL21365766 0.92 MAPT (0.40) KDM4EL3MBTL1ATMHTTMAPT
SCHEMBL21671487 0.92 MAPT (0.40) KDM4EL3MBTL1ATMHTTMAPT
SCHEMBL19769885 0.92 MAPT (0.40) KDM4EL3MBTL1ATMHTTMAPT
SCHEMBL15625707 0.92 MAPT (0.40) KDM4EL3MBTL1ATMHTTMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230255106-A1 ORGANIC ELECTROLUMINESCENT APPARATUS MERCK PATENT GMBH (DE) 2023-08-10 US disclosed
US-20230255106-A1 ORGANIC ELECTROLUMINESCENT APPARATUS MERCK PATENT GMBH (DE) 2023-08-10 US disclosed
WO-2021239772-A1 ORGANIC ELECTROLUMINESCENT APPARATUS MERCK PATENT GMBH (DE) 2021-12-02 WO disclosed
US-10361378-B2 Organic electroluminescent device NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2019-07-23 US disclosed
US-20150325796-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2015-11-12 US disclosed
US-20150325796-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2015-11-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10361378-B2 Organic electroluminescent device ELF3, DDT, LEF1 KDM4E 1228/4885L3MBTL1 74/4885ATM 3768/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.