SCHEMBL17248352

SCHEMBL17248352

c1ccc2c(c1)oc1ccc(-n3c4ccccc4c4cc(-c5cc(-n6c7ccccc7c7ccccc76)cc(-n6c7ccccc7c7ccccc76)c5)ccc43)cc12

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.39
MAPT P10636 3/20 0.39
ALDH1A1 P00352 3/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
NPC1 O15118 2/20 0.39
MEN1 O00255 2/20 0.39
HPGD P15428 2/20 0.39
KMT2A Q03164 2/20 0.39
RAB9A P51151 1/20 0.39
ATM Q13315 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
AHR P35869 2/20 0.36
PLA2G2A P14555 3/20 0.35
PLA2G4A P47712 3/20 0.35
CASP3 P42574 1/20 0.34
SENP7 Q9BQF6 1/20 0.34
SENP6 Q9GZR1 1/20 0.34
CHEK2 O96017 1/20 0.34
EDNRB P24530 1/20 0.33
EDNRA P25101 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25009931 1.00 KDM4E (0.39) KDM4EMAPTALDH1A1SMN1; SMN2NPC1
SCHEMBL27419591 0.97 KDM4E (0.39) KDM4EMAPTALDH1A1SMN1; SMN2NPC1
SCHEMBL10042636 0.96 KDM4E (0.41) KDM4EMAPTALDH1A1SMN1; SMN2NPC1
SCHEMBL17885371 0.96 KDM4E (0.41) KDM4EMAPTALDH1A1SMN1; SMN2NPC1
SCHEMBL10042637 0.96 KDM4E (0.41) KDM4EMAPTALDH1A1SMN1; SMN2NPC1
SCHEMBL2628368 0.95 KDM4E (0.41) KDM4EMAPTALDH1A1SMN1; SMN2NPC1
SCHEMBL2628398 0.95 KDM4E (0.41) KDM4EMAPTALDH1A1SMN1; SMN2NPC1
SCHEMBL11885215 0.95 KDM4E (0.42) KDM4EMAPTALDH1A1SMN1; SMN2NPC1
SCHEMBL17248354 0.95 KDM4E (0.42) KDM4EMAPTALDH1A1SMN1; SMN2NPC1
SCHEMBL18265969 0.95 KDM4E (0.42) KDM4EMAPTALDH1A1SMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220216427-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2022-07-07 US disclosed
US-10361378-B2 Organic electroluminescent device NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2019-07-23 US disclosed
EP-2933851-B1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL & SUMIKIN CHEM CO (JP) 2017-05-10 EP disclosed
US-20150325796-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2015-11-12 US disclosed
US-20150325796-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2015-11-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10361378-B2 Organic electroluminescent device ELF3, DDT, LEF1 KDM4E 1228/4885MAPT 826/4885ALDH1A1 829/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.