Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.55 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.49 |
| ▸ | HPGDS | O60760 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3715714 | 0.88 | KMT2A (0.64) | NSD2KMT2AMAPK8ATMEGLN1 | |
| SCHEMBL3556910 | 0.88 | KMT2A (0.64) | NSD2KMT2AMAPK8ATMEGLN1 | |
| SCHEMBL31026208 | 0.82 | KMT2A (0.61) | NSD2KMT2AMAPK8ATMEGLN1 | |
| SCHEMBL7138975 | 0.82 | KMT2A (0.61) | NSD2KMT2AMAPK8ATMEGLN1 | |
| SCHEMBL8154709 | 0.82 | KMT2A (0.80) | NSD2KMT2AMAPK8ATMEGLN1 | |
| SCHEMBL31026221 | 0.81 | EGLN2 (0.68) | NSD2KMT2AMAPK8ATMRPS6KB1 | |
| SCHEMBL7452205 | 0.81 | KDM4E (0.52) | KMT2AGAAALDH1A1HPGDL3MBTL1 | |
| SCHEMBL31026200 | 0.80 | HTT (0.56) | NSD2KMT2AMAPK8ATMLMNA | |
| SCHEMBL3958929 | 0.79 | KMT2A (0.61) | NSD2KMT2AMAPK8ATMEGLN1 | |
| SCHEMBL15402857 | 0.79 | KDM4E (0.48) | KMT2AALDH1A1HPGDL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109701574-B | Preparation of nitrogen-modified carbon-supported noble metal hydrogenation catalyst and application of nitrogen-modified carbon-supported noble metal hydrogenation catalyst in hydrogenation reaction of pyridine ring compounds | 浙江工业大学 | 2022-04-19 | — | — | CN | claimed |
| CN-116987075-A | Process for preparing pyridine dicarboximide compound | 浙江新和成股份有限公司 | 2023-11-03 | — | — | CN | disclosed |
| CN-109701574-B | Preparation of nitrogen-modified carbon-supported noble metal hydrogenation catalyst and application of nitrogen-modified carbon-supported noble metal hydrogenation catalyst in hydrogenation reaction of pyridine ring compounds | 浙江工业大学 | 2022-04-19 | — | — | CN | disclosed |
| EP-2403831-B1 | SYNTHESIS OF (4aS,7aS)-OCTAHYDRO-1H-PYRROLOÝ3,4-b¨PYRIDINE | ITALIANA SINT SPA (IT) | 2015-05-20 | — | — | EP | disclosed |
| US-8680276-B2 | Synthesis of (4aS,7aS)-octahydro-1H-pyrrolo[3,4-b]pyridine | F.I.S. FABBRICA ITALIANA SINTETICI S.P.A (IT) | 2014-03-25 | — | — | US | disclosed |
| CN-103613592-A | Synthesis method of aromatic ring or aromatic heterocyclic ring-fused amide | DALIAN JOIN KING BIO CHEMICAL TECHNOLOGY CO LTD | 2014-03-05 | — | — | CN | disclosed |
| EP-2403831-A1 | SYNTHESIS OF (4aS,7aS)-OCTAHYDRO-1H-PYRROLOÝ3,4-b¨PYRIDINE | F.I.S. Fabbrica Italiana Sintetici S.p.A. (IT) | 2012-01-11 | — | — | EP | disclosed |
| US-20110137036-A1 | SYNTHESIS OF (4aS,7aS)-OCTAHYDRO-1H-PYRROLO[3,4-b]PYRIDINE | F.I.S. FABBRICA ITALIANA SINTETICI S.P.A (IT) | 2011-06-09 | — | — | US | disclosed |
| WO-2010100215-A1 | SYNTHESIS OF (4aS,7aS)-OCTAHYDRO-1H-PYRROLO[3,4-b]PYRIDINE | F.I.S. FABBRICA ITALIANA SINTETICI S.P.A. (IT) | 2010-09-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110137036-A1 | SYNTHESIS OF (4aS,7aS)-OCTAHYDRO-1H-PYRROLO[3,4-b]PYRIDINE | PDXK, OXA1L, PDK4 | NSD2 4851/4885KMT2A 4545/4885MAPK8 2963/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.