Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.80 |
| ▸ | NSD2 | O96028 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.65 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.63 |
| ▸ | ATM | Q13315 | 1/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | APEX1 | P27695 | 1/20 | 0.59 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | AGER | Q15109 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | ASPH | Q12797 | 1/20 | 0.57 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.57 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3556910 | 0.88 | KMT2A (0.64) | KMT2ANSD2KDM4EMAPK8ATM | |
| SCHEMBL3715714 | 0.88 | KMT2A (0.64) | KMT2ANSD2KDM4EMAPK8ATM | |
| SCHEMBL3182140 | 0.83 | NSD2 (0.68) | KMT2ANSD2KDM4EMAPK8ATM | |
| SCHEMBL28747434 | 0.83 | KMT2A (0.67) | KMT2ANSD2KDM4EAPEX1L3MBTL1 | |
| SCHEMBL1724926 | 0.82 | NSD2 (0.59) | KMT2ANSD2KDM4EMAPK8ATM | |
| SCHEMBL12142857 | 0.82 | NSD2 (0.66) | KMT2ANSD2KDM4EMAPK8ATM | |
| SCHEMBL920392 | 0.82 | NSD2 (0.66) | KMT2ANSD2MAPK8ATMUSP2 | |
| SCHEMBL922492 | 0.82 | NSD2 (0.66) | KMT2ANSD2MAPK8ATMUSP2 | |
| SCHEMBL31569526 | 0.82 | NSD2 (0.66) | KMT2ANSD2KDM4EMAPK8ATM | |
| SCHEMBL13139170 | 0.82 | ATM (0.67) | KMT2ANSD2KDM4EMAPK8ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2000344769-A | PRODUCTION OF N-BENZYLQUINOLINIC ACID IMIDE | TAMA KAGAKU KOGYO KK | 2000-12-12 | — | — | JP | disclosed |
| US-5118677-A | For treating transplant rejection, host vs. draft disease, autoimmune diseases and inflammations; antibody inhibitors | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-06-02 | — | — | US | disclosed |