Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | KIF11 | P52732 | 1/20 | 0.49 |
| ▸ | AHR | P35869 | 1/20 | 0.48 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | HTR1D | P28221 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | UBE2N | P61088 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27438542 | 0.85 | KIF11 (0.58) | KDM4EGAAALDH1A1HPGDTHRB | |
| SCHEMBL26497854 | 0.81 | KDM4E (0.54) | KDM4EGAAALDH1A1MAPTKIF11 | |
| SCHEMBL21376875 | 0.81 | KIF11 (0.62) | KDM4EGAAALDH1A1MAPTKIF11 | |
| SCHEMBL10067359 | 0.79 | KDM4E (0.44) | KDM4EGAAALDH1A1MAPTKIF11 | |
| SCHEMBL13881538 | 0.78 | EIF4A3 (0.60) | KDM4EGAAALDH1A1HPGDTHRB | |
| SCHEMBL22756732 | 0.77 | KIF11 (0.53) | KDM4EGAAALDH1A1HPGDMAPT | |
| SCHEMBL16454837 | 0.76 | F2 (0.56) | KDM4EGAAHPGDKIF11 | |
| SCHEMBL8692313 | 0.76 | KDM4E (0.52) | KDM4EGAAALDH1A1HPGDTHRB | |
| SCHEMBL16688229 | 0.75 | KDM4E (0.57) | KDM4EALDH1A1HPGDTHRBMAPT | |
| SCHEMBL13174592 | 0.75 | ALDH1A1 (0.56) | KDM4EGAAALDH1A1HPGDTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110437126-B | Organocatalytic indole non-activated sp3Method and application for asymmetric functionalization of carbon-hydrogen bond | 香港科技大学深圳研究院 | 2020-11-13 | — | — | CN | disclosed |
| CN-110437126-A | Organic catalysis indoles disactivation sp3The method and application of C-H bond asymmetry function dough | HKUST SHENZHEN RES INSTITUTE | 2019-11-12 | — | — | CN | disclosed |
| US-9708308-B2 | Factor IXa inhibitors | MERCK SHARP DOHME CORP. (US) | 2017-07-18 | — | — | US | disclosed |
| US-9708308-B2 | Factor IXa inhibitors | MERCK SHARP DOHME CORP. (US) | 2017-07-18 | — | — | US | disclosed |
| US-20150322056-A1 | Factor IXa Inhibitors | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2015-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150322056-A1 | Factor IXa Inhibitors | F9, F12, F8 | KDM4E 2107/4885GAA 4102/4885ALDH1A1 3931/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.