Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | AGER | Q15109 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MYC | P01106 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16414490 | 0.85 | ALDH1A1 (0.44) | NAPRTKDM4EALDH1A1TDP1MAPT | |
| SCHEMBL31585844 | 0.83 | NAPRT (0.58) | NAPRTKDM4EALDH1A1TDP1MAPT | |
| SCHEMBL3932427 | 0.83 | NAPRT (0.58) | NAPRTKDM4EALDH1A1TDP1MAPT | |
| SCHEMBL24135918 | 0.81 | KDM4E (0.41) | NAPRTKDM4EALDH1A1TDP1MAPT | |
| SCHEMBL14976530 | 0.81 | NAPRT (0.43) | NAPRTKDM4EALDH1A1TDP1MAPT | |
| SCHEMBL30687291 | 0.81 | PARP1 (0.51) | NAPRTKDM4EALDH1A1TDP1MAPT | |
| Hydrochloric Acid SCHEMBL28886794 | 0.81 | NAPRT (0.56) | NAPRTKDM4EALDH1A1TDP1MAPT | |
| SCHEMBL17857938 | 0.81 | PARP1 (0.51) | NAPRTKDM4EALDH1A1TDP1MAPT | |
| SCHEMBL17854908 | 0.81 | SMN1; SMN2 (0.43) | NAPRTKDM4EALDH1A1TDP1MAPT | |
| SCHEMBL16344365 | 0.81 | TDP1 (0.55) | KDM4EALDH1A1TDP1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018046431-A1 | ACTIVE COMPOUND COMBINATIONS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-03-15 | — | — | WO | disclosed |
| US-20180057462-A1 | Substituted 2-difluoromethyl-nicotin(thio)carboxanilide derivatives and their use as fungicides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-03-01 | — | — | US | disclosed |
| US-20170150717-A1 | Difluoromethyl-nicotinic-indanyl carboxamides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-06-01 | — | — | US | disclosed |
| US-9428459-B2 | Difluoromethyl-nicotinic- tetrahydronaphtyl carboxamides | BAYER CROPSCIENCE AG (DE) | 2016-08-30 | — | — | US | disclosed |
| US-9376391-B2 | Difluoromethyl-nicotinic-tetrahydronaphthyl carboxamides as fungicides | BAYER CROPSCIENCE AG (DE) | 2016-06-28 | — | — | US | disclosed |
| US-20150336896-A1 | DIFLUOROMETHYL-NICOTINIC- TETRAHYDRONAPHTHYL CARBOXAMIDES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2015-11-26 | — | — | US | disclosed |
| US-20150322013-A1 | DIFLUOROMETHYL-NICOTINIC- TETRAHYDRONAPHTYL CARBOXAMIDES | BAYER CROPSCIENCE AG (US) | 2015-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170150717-A1 | Difluoromethyl-nicotinic-indanyl carboxamides | NNMT, NAPRT, NAMPT | NAPRT 2/4885KDM4E 1707/4885ALDH1A1 2673/4885 |
| US-20150322013-A1 | DIFLUOROMETHYL-NICOTINIC- TETRAHYDRONAPHTYL CARBOXAMIDES | NAPRT, NNMT, NAMPT | NAPRT 1/4885KDM4E 2971/4885ALDH1A1 1589/4885 |
| US-20150336896-A1 | DIFLUOROMETHYL-NICOTINIC- TETRAHYDRONAPHTHYL CARBOXAMIDES AS FUNGICIDES | NAPRT, DDT, NAMPT | NAPRT 1/4885KDM4E 1173/4885ALDH1A1 1589/4885 |
| US-20180057462-A1 | Substituted 2-difluoromethyl-nicotin(thio)carboxanilide derivatives and their use as fungicides | NAPRT, NAMPT, NIT2 | NAPRT 1/4885KDM4E 845/4885ALDH1A1 1652/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.