Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29344242 | 0.74 | GRIN2D (0.37) | GPR35KDM4EMEN1ALDH1A1TTR | |
| SCHEMBL11642626 | 0.73 | CA1 (0.43) | GPR35MEN1ALDH1A1TTRKMT2A | |
| SCHEMBL4582714 | 0.73 | GPR35 (0.47) | GPR35ALDH1A1HPGDALOX15MAPK1 | |
| SCHEMBL28702870 | 0.73 | S100A4 (0.40) | GPR35KDM4EMEN1ALDH1A1HPGD | |
| SCHEMBL8224231 | 0.73 | TSHR (0.44) | GPR35ALDH1A1CYP1A2CA1CA2 | |
| Ammonia Solution, Strong SCHEMBL20190529 | 0.72 | GPR35 (0.46) | GPR35MEN1ALDH1A1TTRKMT2A | |
| SCHEMBL17219535 | 0.72 | MAPT (0.36) | ALDH1A1CYP1A2MAPTMAPK1HIF1A | |
| SCHEMBL28683122 | 0.72 | S100A4 (0.39) | GPR35KDM4EMEN1ALDH1A1HPGD | |
| Potassium SCHEMBL30589383 | 0.72 | S100A4 (0.39) | GPR35KDM4EMEN1ALDH1A1HPGD | |
| Ammonia Solution, Strong SCHEMBL28932267 | 0.72 | S100A4 (0.39) | GPR35KDM4EMEN1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9695135-B2 | Therapeutic catechols | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2017-07-04 | — | — | US | disclosed |
| US-9695135-B2 | Therapeutic catechols | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2017-07-04 | — | — | US | disclosed |
| US-20150322022-A1 | THERAPEUTIC CATECHOLS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2015-11-12 | — | — | US | disclosed |
| US-20150322022-A1 | THERAPEUTIC CATECHOLS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2015-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150322022-A1 | THERAPEUTIC CATECHOLS | COMT, SARS1, C5AR1 | GPR35 1319/4885KDM4E 457/4885MEN1 1972/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.