⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22176760 | 0.83 | — | — | |
| SCHEMBL17251313 | 0.82 | — | — | |
| SCHEMBL17754490 | 0.75 | — | — | |
| SCHEMBL19566535 | 0.75 | — | — | |
| SCHEMBL17754512 | 0.75 | — | — | |
| SCHEMBL8752635 | 0.74 | SMPD1 (0.30) | — | |
| SCHEMBL18892768 | 0.74 | SMPD1 (0.30) | — | |
| SCHEMBL8928340 | 0.74 | SMPD1 (0.30) | — | |
| SCHEMBL17369132 | 0.72 | CA2 (0.34) | — | |
| SCHEMBL2742876 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9629867-B2 | Methods and compositions of improved modified siRNA | AM Biotechnologies, Inc. (US) | 2017-04-25 | — | — | US | disclosed |
| US-20150322431-A1 | Methods and Compositions of Improved Modified siRNA | AM BIOTECHNOLOGIES | 2015-11-12 | — | — | US | disclosed |