Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10107071 | 1.00 | JAK2 (0.31) | JAK2JAK1TYK2JAK3TDP1 | |
| SCHEMBL17253449 | 1.00 | JAK2 (0.31) | JAK2JAK1TYK2JAK3TDP1 | |
| SCHEMBL131878 | 1.00 | — | — | |
| SCHEMBL5552795 | 0.97 | — | — | |
| SCHEMBL9647351 | 0.91 | RIPK1 (0.31) | — | |
| SCHEMBL9647335 | 0.91 | RIPK1 (0.31) | — | |
| SCHEMBL19335820 | 0.91 | — | — | |
| SCHEMBL9647344 | 0.91 | RIPK1 (0.31) | — | |
| SCHEMBL29235791 | 0.91 | — | — | |
| SCHEMBL8614566 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015170050-A1 | THERMOPLASTIC AROMATIC POLYESTERS COMPRISING TETRAHYDROFURAN-DIMETHANOL AND FURANDICARBOXYLIC ACID MOTIFS | ROQUETTE FRERES (FR) | 2015-11-12 | — | — | WO | disclosed |
| WO-2015170049-A1 | THERMOPLASTIC AROMATIC POLYESTERS COMPRISING TETRAHYDROFURAN-DIMETHANOL MOTIFS | ROQUETTE FRERES (FR) | 2015-11-12 | — | — | WO | disclosed |