SCHEMBL17252549

SCHEMBL17252549

c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc4oc5ccc(-c6ccc7c(c6)c6cc(-c8ccc9sc%10ccccc%10c9c8)ccc6n7-c6ccccc6)cc5c34)n2)cc1

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 2/20 0.31
PLA2G4A P47712 2/20 0.31
PLA2G10 O15496 1/20 0.31
SIRT2 Q8IXJ6 1/20 0.31
SIRT1 Q96EB6 1/20 0.31
PIM3 Q86V86 1/20 0.30
LMNA P02545 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19039057 0.98 KDM4E (0.32) PLA2G2APLA2G4APLA2G10
SCHEMBL17252758 0.96 KDM4E (0.33) SIRT2SIRT1LMNASMN1; SMN2
SCHEMBL26169123 0.96 KDM4E (0.30)
SCHEMBL26169125 0.96 KDM4E (0.30)
SCHEMBL22257880 0.95 PLA2G10 (0.31) PLA2G2APLA2G4APLA2G10SIRT2SIRT1
SCHEMBL26168457 0.95 KDM4E (0.33) PLA2G2APLA2G4APLA2G10SIRT2SIRT1
SCHEMBL17252694 0.95 PLA2G10 (0.33) PLA2G2APLA2G4APLA2G10SIRT2SIRT1
SCHEMBL26168490 0.95 KDM4E (0.32) PLA2G2APLA2G4APLA2G10SIRT2SIRT1
SCHEMBL26168618 0.94 ALOX5 (0.33)
SCHEMBL26168460 0.94 KDM4E (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11877511-B2 Materials for organic light emitting devices MERCK PATENT GMBH (DE) 2024-01-16 US disclosed
US-11877511-B2 Materials for organic light emitting devices MERCK PATENT GMBH (DE) 2024-01-16 US disclosed
EP-4186898-A1 COMPOSITION FOR ORGANIC ELECTRONIC COMPOUNDS Merck Patent GmbH (DE) 2023-05-31 EP disclosed
US-20230150987-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-05-18 US disclosed
US-20230150987-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-05-18 US disclosed
US-20230138502-A1 MATERIALS FOR ORGANIC LIGHT EMITTING DEVICES MERCK PATENT GMBH (DE) 2023-05-04 US disclosed
US-20230138502-A1 MATERIALS FOR ORGANIC LIGHT EMITTING DEVICES MERCK PATENT GMBH (DE) 2023-05-04 US disclosed
US-20230125939-A1 MATERIALS FOR ORGANIC LIGHT EMITTING DEVICES MERCK PATENT GMBH (DE) 2023-04-27 US disclosed
US-20230125939-A1 MATERIALS FOR ORGANIC LIGHT EMITTING DEVICES MERCK PATENT GMBH (DE) 2023-04-27 US disclosed
US-20200251660-A1 MATERIALS FOR ORGANIC LIGHT EMITTING DEVICES MERCK PATENT GMBH (DE) 2020-08-06 US disclosed
US-20200231578-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2020-07-23 US disclosed
US-20170186965-A1 MATERIALS FOR ORGANIC LIGHT EMITTING DEVICES MERCK PATENT GMBH (DE) 2017-06-29 US disclosed
US-20170186965-A1 MATERIALS FOR ORGANIC LIGHT EMITTING DEVICES MERCK PATENT GMBH (DE) 2017-06-29 US disclosed
WO-2015169412-A1 MATERIALS FOR ORGANIC LIGHT EMITTING DEVICES MERCK PATENT GMBH (DE) 2015-11-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170186965-A1 MATERIALS FOR ORGANIC LIGHT EMITTING DEVICES DDT, ESD, ETFA PLA2G2A 3940/4885PLA2G4A 3627/4885PLA2G10 4270/4885
US-20230125939-A1 MATERIALS FOR ORGANIC LIGHT EMITTING DEVICES DDT, ESD, ETFA PLA2G2A 3940/4885PLA2G4A 3627/4885PLA2G10 4270/4885
US-20230138502-A1 MATERIALS FOR ORGANIC LIGHT EMITTING DEVICES DDT, ESD, ETFA PLA2G2A 3940/4885PLA2G4A 3627/4885PLA2G10 4270/4885
US-20200251660-A1 MATERIALS FOR ORGANIC LIGHT EMITTING DEVICES DDT, ESD, ETFA PLA2G2A 3940/4885PLA2G4A 3627/4885PLA2G10 4270/4885
US-20230150987-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES SLCO2B1, SLCO2A1, SLCO1B3 PLA2G2A 4589/4885PLA2G4A 4764/4885PLA2G10 4812/4885
US-11877511-B2 Materials for organic light emitting devices DDT, ESD, ETFA PLA2G2A 3940/4885PLA2G4A 3627/4885PLA2G10 4270/4885
US-20200231578-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES SLCO2B1, SLCO2A1, SLCO1B3 PLA2G2A 4589/4885PLA2G4A 4764/4885PLA2G10 4812/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.