Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APAF1 | O14727 | 4/20 | 0.35 |
| ▸ | MITF | O75030 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.33 |
| ▸ | MAPT | P10636 | 7/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.33 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.33 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.32 |
| ▸ | CASP3 | P42574 | 3/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15039579 | 0.92 | MAPT (0.34) | APAF1MITFTDP1ALDH1A1MAPT | |
| SCHEMBL15020098 | 0.92 | MAPT (0.34) | APAF1MITFTDP1ALDH1A1MAPT | |
| SCHEMBL15020099 | 0.92 | MAPT (0.34) | APAF1MITFTDP1ALDH1A1MAPT | |
| SCHEMBL15020129 | 0.91 | ALDH1A1 (0.37) | APAF1MITFTDP1ALDH1A1MAPT | |
| SCHEMBL15020128 | 0.91 | ALDH1A1 (0.37) | APAF1MITFTDP1ALDH1A1MAPT | |
| SCHEMBL17253269 | 0.91 | ALDH1A1 (0.37) | APAF1MITFTDP1ALDH1A1MAPT | |
| SCHEMBL17253298 | 0.88 | ALDH1A1 (0.35) | APAF1MITFTDP1ALDH1A1MAPT | |
| SCHEMBL15020117 | 0.88 | ALDH1A1 (0.35) | APAF1MITFTDP1ALDH1A1MAPT | |
| SCHEMBL15020118 | 0.88 | ALDH1A1 (0.35) | APAF1MITFTDP1ALDH1A1MAPT | |
| SCHEMBL15019814 | 0.87 | APAF1 (0.39) | APAF1MITFTDP1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150320660-A1 | TRIAROMATIC AZOMETHINE DIRECT DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH DYE, METHOD OF IMPLEMENTATION AND USE | L'OREAL (FR) | 2015-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150320660-A1 | TRIAROMATIC AZOMETHINE DIRECT DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH DYE, METHOD OF IMPLEMENTATION AND USE | KRT18, MKI67, CDC73 | APAF1 3032/4885MITF 1068/4885TDP1 1636/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.