Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 5/20 | 0.62 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17253572 | 0.90 | DHODH (0.77) | DHODHRORCNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL247329 | 0.77 | DHODH (1.00) | DHODHNPC1RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL247030 | 0.72 | DHODH (0.77) | DHODHNPC1RAB9ASMN1; SMN2MRGPRX4 | |
| SCHEMBL248244 | 0.72 | DHODH (0.71) | DHODHMRGPRX4NPSR1EGFR | |
| SCHEMBL290914 | 0.71 | DHODH (0.89) | DHODHNPC1RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL13743194 | 0.71 | DHODH (0.54) | DHODHRORCGRM4NPC1RAB9A | |
| SCHEMBL247876 | 0.70 | DHODH (0.65) | DHODHGRM4MRGPRX4NPSR1LMNA | |
| SCHEMBL18418380 | 0.70 | DHODH (0.73) | DHODHNPC1RAB9ANPSR1LMNA | |
| SCHEMBL3918407 | 0.69 | DHODH (0.71) | DHODHNPC1RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL517712 | 0.66 | DHODH (0.85) | DHODHNPC1RAB9ASMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015169944-A1 | COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS | PANOPTES PHARMA GES.M.B.H. (AT) | 2015-11-12 | — | — | WO | disclosed |