Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 10/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.45 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13743194 | 0.91 | DHODH (0.54) | DHODHSGMS2MRGPRX4STK39GRM4 | |
| SCHEMBL19417319 | 0.88 | DHODH (0.50) | DHODHSGMS2MRGPRX4STK39GRM4 | |
| SCHEMBL247030 | 0.87 | DHODH (0.77) | DHODHNPSR1MRGPRX4 | |
| SCHEMBL248244 | 0.84 | DHODH (0.71) | DHODHNPSR1MRGPRX4 | |
| SCHEMBL17253572 | 0.80 | DHODH (0.77) | DHODHNPSR1MRGPRX4 | |
| SCHEMBL247329 | 0.78 | DHODH (1.00) | DHODHNPSR1SGMS2 | |
| SCHEMBL290914 | 0.73 | DHODH (0.89) | DHODHNPSR1SGMS2 | |
| SCHEMBL3925201 | 0.72 | EPHX2 (0.60) | DHODH | |
| SCHEMBL16239897 | 0.70 | MRGPRX4 (0.62) | MRGPRX4 | |
| SCHEMBL17254039 | 0.70 | DHODH (0.62) | DHODHNPSR1MRGPRX4LMNAGRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8653138-B2 | Calcium salts of compounds as anti-inflammatory, immunomodulatory and anti-proliferatory agents | 4SC MG (DE) | 2014-02-18 | — | — | US | claimed |
| EP-2966058-B1 | NOVEL CALCIUM SALTS OF COMPOUND AS ANTI-INFLAMMATORY, IMMUNOMODULATORY AND ANTI-PROLIFERATORY AGENTS | 4SC AG (DE) | 2017-10-04 | — | — | EP | disclosed |
| EP-2966058-B1 | NOVEL CALCIUM SALTS OF COMPOUND AS ANTI-INFLAMMATORY, IMMUNOMODULATORY AND ANTI-PROLIFERATORY AGENTS | 4SC AG (DE) | 2017-10-04 | — | — | EP | disclosed |
| EP-2966058-A1 | NOVEL CALCIUM SALTS OF COMPOUND AS ANTI-INFLAMMATORY, IMMUNOMODULATORY AND ANTI-PROLIFERATORY AGENTS | 4SC AG (DE) | 2016-01-13 | — | — | EP | disclosed |
| EP-2588446-B1 | NOVEL CALCIUM SALTS OF COMPOUND AS ANTI-INFLAMMATORY, IMMUNOMODULATORY AND ANTI-PROLIFERATORY AGENTS | 4SC AG (DE) | 2015-09-09 | — | — | EP | disclosed |
| US-8653138-B2 | Calcium salts of compounds as anti-inflammatory, immunomodulatory and anti-proliferatory agents | 4SC MG (DE) | 2014-02-18 | — | — | US | disclosed |
| US-8653138-B2 | Calcium salts of compounds as anti-inflammatory, immunomodulatory and anti-proliferatory agents | 4SC MG (DE) | 2014-02-18 | — | — | US | disclosed |
| EP-2588446-A1 | NOVEL CALCIUM SALTS OF COMPOUND AS ANTI-INFLAMMATORY, IMMUNOMODULATORY AND ANTI-PROLIFERATORY AGENTS | 4SC AG (DE) | 2013-05-08 | — | — | EP | disclosed |
| US-20120035175-A1 | Novel salts as Anti-Inflammatory, Immunomodulatory and Anti-Proliferatory Agents | 4SC AG (DE) | 2012-02-09 | — | — | US | disclosed |
| US-20120035175-A1 | Novel salts as Anti-Inflammatory, Immunomodulatory and Anti-Proliferatory Agents | 4SC AG (DE) | 2012-02-09 | — | — | US | disclosed |
| US-20120035175-A1 | Novel salts as Anti-Inflammatory, Immunomodulatory and Anti-Proliferatory Agents | 4SC AG (DE) | 2012-02-09 | — | — | US | disclosed |
| US-20120029034-A1 | Novel calcium salts of Compound as Anti-Inflammatory, Immunomodulatory and Anti-Proliferatory Agents | 4SC AG (DE) | 2012-02-02 | — | — | US | disclosed |
| US-20120029034-A1 | Novel calcium salts of Compound as Anti-Inflammatory, Immunomodulatory and Anti-Proliferatory Agents | 4SC AG (DE) | 2012-02-02 | — | — | US | disclosed |
| WO-2012001148-A1 | NOVEL CALCIUM SALTS OF COMPOUND AS ANTI-INFLAMMATORY, IMMUNOMODULATORY AND ANTI-PROLIFERATORY AGENTS | 4SC AG (DE) | 2012-01-05 | — | — | WO | disclosed |
| US-7423057-B2 | Compounds as anti-inflammatory, immunomodulatory and anti-proliferatory agents | 4SC AG (DE) | 2008-09-09 | — | — | US | disclosed |
| US-7423057-B2 | Compounds as anti-inflammatory, immunomodulatory and anti-proliferatory agents | 4SC AG (DE) | 2008-09-09 | — | — | US | disclosed |
| US-7176241-B2 | Compounds as anti-inflammatory, immunomodulatory and anti-proliferatory agents | 4SC AG (DE) | 2007-02-13 | — | — | US | disclosed |
| US-7176241-B2 | Compounds as anti-inflammatory, immunomodulatory and anti-proliferatory agents | 4SC AG (DE) | 2007-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120029034-A1 | Novel calcium salts of Compound as Anti-Inflammatory, Immunomodulatory and Anti-Proliferatory Agents | PPARD, PPARG, PPARA | DHODH 3085/4885NPSR1 779/4885SGMS2 978/4885 |
| US-20120035175-A1 | Novel salts as Anti-Inflammatory, Immunomodulatory and Anti-Proliferatory Agents | ARG1, CD14, RXRG | DHODH 1882/4885NPSR1 1073/4885SGMS2 327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.