Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 6/20 | 0.54 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 10/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 9/20 | 0.44 |
| ▸ | CASP1 | P29466 | 8/20 | 0.44 |
| ▸ | CASP7 | P55210 | 6/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 6/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18057376 | 0.84 | HRH4 (0.51) | HTR3AHRH4ALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL19365189 | 0.84 | HTR3A (0.51) | HTR3AHRH4ALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL20078423 | 0.83 | HTR3A (0.50) | HTR3AHRH4ALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL18057386 | 0.80 | HRH4 (0.47) | HTR3AHRH4ALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL17255015 | 0.80 | HRH4 (0.47) | HTR3AHRH4ALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL18057370 | 0.77 | HRH4 (0.44) | HTR3AHRH4ALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL17255050 | 0.76 | HRH4 (0.51) | HTR3AHRH4HTR3EHTR3BHTR3D | |
| SCHEMBL18057375 | 0.75 | KDM4E (0.46) | HTR3AHRH4ALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL17255020 | 0.72 | NPSR1 (0.44) | ALDH1A1CYP1A2HSD17B10CASP1CASP7 | |
| SCHEMBL603314 | 0.72 | HTR3A (1.00) | HTR3AHRH4ALDH1A1CYP1A2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015172123-A1 | NOVEL COMPOSITIONS, USES AND METHODS FOR MAKING THEM | HADDACH MUSTAPHA (US) | 2015-11-12 | — | — | WO | disclosed |