Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 5/20 | 0.50 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 11/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 10/20 | 0.41 |
| ▸ | CASP1 | P29466 | 8/20 | 0.41 |
| ▸ | CASP7 | P55210 | 6/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 7/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20078425 | 0.83 | MKNK1 (0.46) | HTR3AHRH4 | |
| SCHEMBL18057396 | 0.83 | HTR3A (0.48) | HTR3AHRH4ALDH1A1CYP1A2KMT2A | |
| SCHEMBL17255045 | 0.83 | HTR3A (0.54) | HTR3AHRH4ALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL20078427 | 0.82 | CAMK1D (0.43) | — | |
| SCHEMBL20078410 | 0.82 | DYRK1A (0.41) | HRH4CYP2D6 | |
| SCHEMBL23160983 | 0.81 | HRH4 (0.51) | HTR3AHRH4ALDH1A1CYP1A2HTR3E | |
| SCHEMBL19365189 | 0.80 | HTR3A (0.51) | HTR3AHRH4ALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL18057376 | 0.80 | HRH4 (0.51) | HTR3AHRH4ALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL17255017 | 0.80 | HRH4 (0.44) | HTR3AHRH4ALDH1A1CYP1A2KMT2A | |
| SCHEMBL20078412 | 0.79 | BRD4 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9951066-B2 | Compositions, uses and methods for making them | Pimera, Inc. (US) | 2018-04-24 | — | — | US | disclosed |