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Sugi Predict / Compounds / SCHEMBL172553

SCHEMBL172553

SCHEMBL172553

C=CC(=O)Oc1ccc(N(c2ccccc2)c2ccc(COC(=O)C(=C)C)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ THRB P10828 3/20 0.48
▸ ELANE P08246 1/20 0.41
▸ ALDH1A1 P00352 3/20 0.38
▸ MAPT P10636 2/20 0.37
▸ HPGD P15428 1/20 0.37
▸ PDE6D O43924 1/20 0.36
▸ ALOX5 P09917 1/20 0.36
▸ PTGS1 P23219 1/20 0.36
▸ PTGS2 P35354 1/20 0.36
▸ NR1H4 Q96RI1 1/20 0.36
▸ HCAR2 Q8TDS4 1/20 0.35
▸ NPSR1 Q6W5P4 1/20 0.35
▸ RAB9A P51151 3/20 0.35
▸ L3MBTL1 Q9Y468 2/20 0.35
▸ NPC1 O15118 2/20 0.35
▸ SMN1; SMN2 Q16637 2/20 0.35
▸ POLB P06746 1/20 0.35
▸ APEX1 P27695 1/20 0.35
▸ HTT P42858 1/20 0.35
▸ TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11987094 0.94 THRB (0.45) THRBELANEALDH1A1MAPTSMN1; SMN2
SCHEMBL172500 0.94 THRB (0.45) THRBELANEALDH1A1MAPTHPGD
SCHEMBL11987078 0.92 ELANE (0.46) THRBELANEALDH1A1MAPTHPGD
SCHEMBL172498 0.92 ALDH1A1 (0.41) THRBALDH1A1MAPTHPGDHCAR2
SCHEMBL11987093 0.91 THRB (0.44) THRBELANEALDH1A1MAPTHPGD
SCHEMBL11987080 0.91 THRB (0.48) THRBELANEALDH1A1MAPTRAB9A
SCHEMBL172208 0.90 ELANE (0.51) ELANEALDH1A1MAPTHPGDALOX5
SCHEMBL11987105 0.89 THRB (0.43) THRBELANEMAPTRAB9ANPC1
SCHEMBL11987104 0.89 THRB (0.40) THRBALDH1A1MAPTHPGDHCAR2
SCHEMBL11987076 0.88 THRB (0.51) THRBALDH1A1MAPTHPGDPDE6D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8927183-B2 Electrophotographic photoreceptor, method for preparing the electrophotographic photoreceptor, and image forming method and apparatus and process cartridge using the electrophotographic photoreceptor RICOH COMPANY, LTD. (JP) 2015-01-06 — — US disclosed
US-8927183-B2 Electrophotographic photoreceptor, method for preparing the electrophotographic photoreceptor, and image forming method and apparatus and process cartridge using the electrophotographic photoreceptor RICOH COMPANY, LTD. (JP) 2015-01-06 — — US disclosed
US-8335456-B2 Image forming apparatus, image forming method, and process cartridge RICOH COMPANY, LTD. (JP) 2012-12-18 — — US disclosed
US-8335456-B2 Image forming apparatus, image forming method, and process cartridge RICOH COMPANY, LTD. (JP) 2012-12-18 — — US disclosed
US-8247143-B2 Photoreceptor, image formation method, image forming apparatus and process cartridge RICOH COMPANY, LTD. (JP) 2012-08-21 — — US disclosed
US-8247143-B2 Photoreceptor, image formation method, image forming apparatus and process cartridge RICOH COMPANY, LTD. (JP) 2012-08-21 — — US disclosed
EP-1847881-B1 Image forming apparatus, image forming method, and process cartridge RICOH CO LTD (JP) 2012-03-07 — — EP disclosed
US-8043773-B2 surface layer having a good anti-abrasion property, good electric characteristics and a good cleaning property for a spherical toner; photosensitive layer on an electroconductive substrate; Particulates having a needle form are dispersed in the surface layer of the photosensitive layer RICOH COMPANY, LIMITED (JP) 2011-10-25 — — US disclosed
US-8043773-B2 surface layer having a good anti-abrasion property, good electric characteristics and a good cleaning property for a spherical toner; photosensitive layer on an electroconductive substrate; Particulates having a needle form are dispersed in the surface layer of the photosensitive layer RICOH COMPANY, LIMITED (JP) 2011-10-25 — — US disclosed
US-7985520-B2 Photoreceptor, image formation method, image forming apparatus and process cartridge RICOH COMPANY, LTD. (JP) 2011-07-26 — — US disclosed
US-20080318142-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, METHOD FOR PREPARING THE ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND IMAGE FORMING METHOD AND APPARATUS AND PROCESS CARTRIDGE USING THE ELECTROPHOTOGRAPHIC PHOTORECEPTOR RICOH COMPANY, LTD. (JP) 2008-12-25 — — US disclosed
US-7449272-B2 Electrophotographic photoreceptor and method of preparing the photoreceptor, and image forming method, image forming apparatus and process cartridge therefor using the photoreceptor RICOH COMPANY, LTD. (JP) 2008-11-11 — — US disclosed
US-7449272-B2 Electrophotographic photoreceptor and method of preparing the photoreceptor, and image forming method, image forming apparatus and process cartridge therefor using the photoreceptor RICOH COMPANY, LTD. (JP) 2008-11-11 — — US disclosed
US-20080241716-A1 IMAGE FORMING APPARATUS, IMAGE FORMING METHOD AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2008-10-02 — — US disclosed
US-20080241716-A1 IMAGE FORMING APPARATUS, IMAGE FORMING METHOD AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2008-10-02 — — US disclosed
US-20080153021-A1 IMAGE BEARING MEMBER, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE RICOH COMPANY LIMITED (JP) 2008-06-26 — — US disclosed
US-20080153021-A1 IMAGE BEARING MEMBER, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE RICOH COMPANY LIMITED (JP) 2008-06-26 — — US disclosed
US-20070297836-A1 IMAGE FORMING APPARATUS, IMAGE FORMING METHOD, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2007-12-27 — — US disclosed
US-20070297836-A1 IMAGE FORMING APPARATUS, IMAGE FORMING METHOD, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2007-12-27 — — US disclosed
EP-1847881-A2 Image forming apparatus, image forming method, and process cartridge Ricoh Company, Ltd. (JP) 2007-10-24 — — EP disclosed