Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | TACR2 | P21452 | 1/20 | 0.46 |
| ▸ | FDPS | P14324 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | UBE2N | P61088 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15952102 | 0.83 | TACR2 (0.60) | ALDH1A1MAPTCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL29446267 | 0.82 | TACR2 (0.62) | ALDH1A1MAPTHPGDTACR2FDPS | |
| SCHEMBL584489 | 0.82 | TACR2 (0.62) | ALDH1A1MAPTHPGDTACR2FDPS | |
| SCHEMBL5217355 | 0.82 | TACR2 (0.54) | ALDH1A1TACR2SMN1; SMN2MAOAMAOB | |
| SCHEMBL5222536 | 0.81 | TACR2 (0.50) | ALDH1A1MAPTTACR2SMN1; SMN2MAOA | |
| SCHEMBL5217306 | 0.81 | TACR2 (0.50) | ALDH1A1MAPTHPGDTACR2SMN1; SMN2 | |
| SCHEMBL15953289 | 0.80 | TACR2 (0.52) | ALDH1A1MAPTCYP1A2CYP2C9HPGD | |
| SCHEMBL15952860 | 0.80 | FDPS (0.60) | ALDH1A1MAPTCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL5213944 | 0.80 | TACR2 (0.54) | ALDH1A1MAPTTACR2FDPSSMN1; SMN2 | |
| SCHEMBL9077155 | 0.80 | TACR2 (0.54) | ALDH1A1MAPTTACR2FDPSSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2944626-B1 | MR IMAGING DIAGNOSTIC AGENT FOR INTRACTABLE NEUROLOGICAL DISEASE | UNIV SHIGA MEDICAL SCIENCE (JP) | 2018-10-10 | — | — | EP | disclosed |
| US-20150352232-A1 | MR IMAGING DIAGNOSTIC AGENT FOR INTRACTABLE NEUROLOGICAL DISEASE | SHIGA UNIVERSITY OF MEDICAL SCIENCE (JP) | 2015-12-10 | — | — | US | disclosed |
| EP-2944626-A1 | MR IMAGING DIAGNOSTIC AGENT FOR INTRACTABLE NEUROLOGICAL DISEASE | Shiga University Of Medical Science (JP) | 2015-11-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150352232-A1 | MR IMAGING DIAGNOSTIC AGENT FOR INTRACTABLE NEUROLOGICAL DISEASE | TARDBP, FUS, SNCA | ALDH1A1 4676/4885MAPT 4/4885CYP1A2 4841/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.