Sugi Predict

Sugi Predict / Compounds / SCHEMBL584489

SCHEMBL584489

SCHEMBL584489

O=Cc1ccc(OCc2ccccc2)c(OCc2ccccc2)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TACR2 P21452 1/20 0.62
▸ MAOA P21397 1/20 0.61
▸ MAOB P27338 1/20 0.61
▸ ALDH1A1 P00352 6/20 0.59
▸ SMN1; SMN2 Q16637 3/20 0.59
▸ LMNA P02545 2/20 0.58
▸ GSK3B P49841 1/20 0.58
▸ KDM4E B2RXH2 1/20 0.58
▸ KMT2A Q03164 2/20 0.57
▸ POLB P06746 1/20 0.57
▸ UBE2N P61088 1/20 0.57
▸ SIRT2 Q8IXJ6 1/20 0.57
▸ MAPT P10636 4/20 0.54
▸ NPC1 O15118 2/20 0.54
▸ RAB9A P51151 2/20 0.54
▸ HTT P42858 2/20 0.54
▸ ADAMTS5 Q9UNA0 1/20 0.53
▸ L3MBTL1 Q9Y468 1/20 0.53
▸ PDCD1 Q15116 1/20 0.52
▸ CD274 Q9NZQ7 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29446267 1.00 TACR2 (0.62) TACR2MAOAMAOBALDH1A1SMN1; SMN2
SCHEMBL1609108 0.92 TACR2 (0.75) TACR2MAOAMAOBALDH1A1SMN1; SMN2
SCHEMBL662145 0.92 TACR2 (0.75) TACR2MAOAMAOBALDH1A1SMN1; SMN2
SCHEMBL29721221 0.91 TACR2 (0.54) TACR2MAOAMAOBALDH1A1SMN1; SMN2
SCHEMBL5216320 0.91 TACR2 (0.78) TACR2MAOAMAOBALDH1A1SMN1; SMN2
SCHEMBL5213944 0.91 TACR2 (0.54) TACR2MAOAMAOBALDH1A1SMN1; SMN2
SCHEMBL9077155 0.91 TACR2 (0.54) TACR2MAOAMAOBALDH1A1SMN1; SMN2
SCHEMBL5215156 0.91 TACR2 (0.61) TACR2MAOAMAOBALDH1A1SMN1; SMN2
SCHEMBL29377794 0.91 ALDH1A1 (0.65) TACR2MAOAMAOBALDH1A1SMN1; SMN2
SCHEMBL752160 0.91 ALDH1A1 (0.65) TACR2MAOAMAOBALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 429 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117924143-A Preparation method of 5, 6-dihydroxyindole 北京成宇化工有限公司 2024-04-26 — — CN claimed
US-11896670-B2 Synthesis routes to access MDMA prodrugs by using controlled and non-controlled intermediates Mind Medicine, Inc. (US) 2024-02-13 — — US claimed
CN-113896642-A Synthetic method of 2- ((3, 4-bis (benzyloxy) benzyl) amino) ethanol 山西永津集团有限公司 2022-01-07 — — CN claimed
CN-113880749-A Preparation method and application of compound JNc-463 江南大学 2022-01-04 — — CN claimed
CN-111233631-A Method for preparing 3, 4-dihydroxy phenethyl alcohol 辽宁东科药业有限公司 2020-06-05 — — CN claimed
US-20110046259-A1 UV-ABSORBERS FOR OPHTHALMIC LENS MATERIALS ALCON, INC. (CH) 2011-02-24 — — US claimed
US-20100048920-A1 Preparation of (+)-Catechin, (-)-Epicatechin, (-)-Catechin, and (+)-Epicatechin and Their 5,7,3',4'-Tetra-O-Benzyl Analogues MARS, INCORPORATED (US) 2010-02-25 — — US claimed
EP-1896443-A1 PREPARATION OF (+)-CATECHIN, (-)-EPICATECHIN, (-)-CATECHIN, (+)-EPICATECHIN, AND THEIR 5,7,3',4'-TETRA-O-BENZYL ANALOGUES MARS, INCORPORATED (US) 2008-03-12 — — EP claimed
WO-2007002877-A1 PREPARATION OF (+)-CATECHIN, (-)-EPICATECHIN, (-)-CATECHIN, (+)-EPICATECHIN, AND THEIR 5,7,3',4'-TETRA-O-BENZYL ANALOGUES MARS, INCORPORATED (US) 2007-01-04 — — WO claimed
US-6797745-B1 Hot melt inks containing styrene or terpene polymers XEROX CORPORATION 2004-09-28 — — US claimed
US-6780900-B1 ALDEHYDE COPOLYMER INK VEHICLE, A NONPOLYMERIC ALDEHYDE VISCOSITY MODIFIER, COLORANT, AN OPTIONAL CONDUCTIVITY ENHANCING AGENT, AN OPTIONAL ANTIOXIDANT, AND AN OPTIONAL UV ABSORBER XEROX CORPORATION 2004-08-24 — — US claimed
WO-1999052936-A2 ARGININE PEPTIDE ANALOGS USEFUL AS FIBROBLAST GROWTH FACTOR ANTAGONISTS EISAI CO., LTD. (JP) 1999-10-21 — — WO claimed
US-5731344-A DIABETES, ATHEROSCLEROSIS, ARTERIOSCLEROSIS; INHIBITORS OF ADVANCED GLYCOSYLATION ENDPRODUCTS BOEHRINGER MANNHEIM GMBH (DE) 1998-03-24 — — US claimed
EP-0075629-A1 Imidazole derivatives, their preparation, and their pharmaceutical compositions Sumitomo Chemical Industries Ltd. (JP) 1983-04-06 — — EP claimed
JP-2270812-A — — None — — JP disclosed
EP-3828163-B1 NOVEL P62 LIGAND COMPOUND, AND COMPOSITION FOR PREVENTING, ALLEVIATING, OR TREATING PROTEINOPATHIES COMPRISING SAME AUTOTAC INC (KR) 2026-05-20 — — EP disclosed
EP-3828164-B1 NOVEL AUTOPHAGY-TARGETING CHIMERA (AUTOTAC) COMPOUND, AND COMPOSITION FOR PREVENTING, ALLEVIATING, OR TREATING DISEASES THROUGH TARGET PROTEIN DEGRADATION COMPRISING SAME AUTOTAC INC (KR) 2025-10-29 — — EP disclosed
US-3962220-A ONE-STEP, AROMATIC ALDEHYDES, ACETIC ACID E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-06-08 — — US disclosed
US-3962221-A CONDENSATION, REDUCTION, OXIDATION E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-06-08 — — US disclosed
US-3935214-A ANTICOAGULANT DONAU-PHARMAZIE GESELLSCHAFT M.B.H. (OE) 1976-01-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100048920-A1 Preparation of (+)-Catechin, (-)-Epicatechin, (-)-Catechin, and (+)-Epicatechin and Their 5,7,3',4'-Tetra-O-Benzyl Analogues HAAO, TES, HPD TACR2 888/4885MAOA 1218/4885MAOB 882/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.