Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.74 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.69 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA7 | P43166 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4316847 | 0.85 | PDE4B (1.00) | PDE4BPDE4DNPSR1P2RY12RAB9A | |
| SCHEMBL6070491 | 0.85 | PDE4B (0.73) | PDE4BPDE4DNPSR1P2RY12RAB9A | |
| SCHEMBL30900068 | 0.84 | PDE4B (0.71) | PDE4BPDE4DNPSR1P2RY12RAB9A | |
| SCHEMBL6069548 | 0.82 | PDE4D (1.00) | PDE4BPDE4DNPSR1P2RY12RAB9A | |
| SCHEMBL16857585 | 0.81 | LMNA (0.56) | PDE4BPDE4DNPSR1RAB9ANPC1 | |
| SCHEMBL6070168 | 0.81 | PDE4B (0.67) | PDE4BPDE4DNPSR1P2RY12RAB9A | |
| SCHEMBL20604097 | 0.80 | PDE4B (0.62) | PDE4BPDE4DNPSR1P2RY12RAB9A | |
| SCHEMBL123446 | 0.77 | PDE4D (0.67) | PDE4BPDE4DNPSR1P2RY12RAB9A | |
| SCHEMBL6070059 | 0.76 | PDE4D (0.80) | PDE4BPDE4DNPSR1P2RY12RAB9A | |
| SCHEMBL26659337 | 0.76 | PDE4D (0.66) | PDE4BPDE4DNPSR1P2RY12RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2669274-B1 | TOPICAL ANTIFUNGAL AGENT | MEIJI SEIKA PHARMA CO LTD (JP) | 2015-11-18 | — | — | EP | claimed |