Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | TYMS | P04818 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13177010 | 0.83 | CYP2A6 (0.66) | CYP2A6ALDH1A1MAPTPKMTP53 | |
| SCHEMBL6599322 | 0.79 | CYP2A6 (0.46) | CYP2A6SIGMAR1DYRK1AMRGPRX4SLC6A2 | |
| SCHEMBL1894396 | 0.79 | CYP2A6 (0.71) | CYP2A6ALDH1A1TDP1TSHRMRGPRX4 | |
| SCHEMBL16693064 | 0.75 | ALDH1A1 (0.52) | CYP2A6ALDH1A1MAPTPKM | |
| SCHEMBL11766607 | 0.75 | RELA (0.55) | CYP2A6ALDH1A1MAPT | |
| SCHEMBL9113662 | 0.72 | CYP2A6 (0.37) | CYP2A6SIGMAR1 | |
| SCHEMBL16709693 | 0.72 | CYP2A6 (0.51) | CYP2A6ALDH1A1TSHRDYRK1A | |
| SCHEMBL19526466 | 0.72 | CYP2A6 (0.40) | CYP2A6SIGMAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2056161 | 0.72 | CYP2A6 (0.40) | CYP2A6ALDH1A1SIGMAR1MRGPRX4SLC6A2 | |
| SCHEMBL29434184 | 0.71 | ALDH1A1 (0.59) | ALDH1A1MAPTPKMTP53TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9394273-B2 | Therapeutic prostaglandin receptor agonists | ALLERGAN, INC. (US) | 2016-07-19 | — | — | US | disclosed |
| US-9394273-B2 | Therapeutic prostaglandin receptor agonists | ALLERGAN, INC. (US) | 2016-07-19 | — | — | US | disclosed |
| US-9394273-B2 | Therapeutic prostaglandin receptor agonists | ALLERGAN, INC. (US) | 2016-07-19 | — | — | US | disclosed |
| US-20150329518-A1 | THERAPEUTIC PROSTAGLANDIN RECEPTOR AGONISTS | ALLERGAN, INC. | 2015-11-19 | — | — | US | disclosed |
| US-20150329518-A1 | THERAPEUTIC PROSTAGLANDIN RECEPTOR AGONISTS | ALLERGAN, INC. | 2015-11-19 | — | — | US | disclosed |
| US-20150329518-A1 | THERAPEUTIC PROSTAGLANDIN RECEPTOR AGONISTS | ALLERGAN, INC. | 2015-11-19 | — | — | US | disclosed |
| WO-2015175984-A1 | THERAPEUTIC PROSTAGLANDIN RECEPTOR AGONISTS | ALLERGAN, INC. (US) | 2015-11-19 | — | — | WO | disclosed |
| WO-2015175984-A1 | THERAPEUTIC PROSTAGLANDIN RECEPTOR AGONISTS | ALLERGAN, INC. (US) | 2015-11-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150329518-A1 | THERAPEUTIC PROSTAGLANDIN RECEPTOR AGONISTS | PTGIR, PTGDR, PTGFR | CYP2A6 1136/4885ALDH1A1 972/4885MAPT 2854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.