Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSG | P08311 | 2/20 | 0.53 |
| ▸ | CMA1 | P23946 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 2/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL132752 | 0.87 | KMT2A (0.51) | CTSGCMA1GAAPPARDPPARA | |
| SCHEMBL135269 | 0.85 | GAA (0.53) | CTSGCMA1GAATSHRPPARD | |
| SCHEMBL129490 | 0.85 | CMA1 (0.54) | CTSGCMA1GAATSHRALDH1A1 | |
| SCHEMBL133340 | 0.81 | GAA (0.50) | CTSGCMA1GAATSHRALDH1A1 | |
| SCHEMBL1932116 | 0.77 | PPARD (0.54) | CTSGCMA1GAAPPARDPPARA | |
| SCHEMBL3552039 | 0.75 | CA1 (0.50) | CTSGCMA1GAAALDH1A1LMNA | |
| SCHEMBL133701 | 0.74 | KMT2A (0.53) | CTSGCMA1GAAALDH1A1HPGD | |
| SCHEMBL12798455 | 0.74 | PPARD (0.48) | CTSGCMA1GAAPPARDPPARA | |
| SCHEMBL3555407 | 0.74 | CTSG (0.44) | CTSGCMA1GAAALDH1A1HPGD | |
| SCHEMBL134036 | 0.74 | MRGPRX4 (0.48) | CTSGCMA1GAAPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1542667-B1 | UREIDO SUBSTITUTED BENZOIC ACID COMPOUNDS AND THEIR USE FOR NONSENSE SUPPRESSION AND THE TREATMENT OF DISEASE | PTC THERAPEUTICS INC (US) | 2012-03-07 | — | — | EP | disclosed |