Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 3/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1729000 | 0.88 | CA2 (0.45) | GBA1OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL1729210 | 0.88 | CA2 (0.45) | GBA1OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL9955881 | 0.87 | GBA1 (0.35) | GBA1 | |
| SCHEMBL22694855 | 0.82 | HRH1 (0.34) | GBA1IDO1TDO2CES2CES1 | |
| SCHEMBL1727640 | 0.82 | SLC6A4 (0.42) | GBA1OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL1727838 | 0.82 | SLC6A4 (0.42) | GBA1OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL12261531 | 0.82 | SLC6A4 (0.42) | GBA1OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL4452204 | 0.81 | GBA1 (0.36) | GBA1IDO1TDO2CES2CES1 | |
| SCHEMBL12056796 | 0.80 | AOC3 (0.44) | GBA1OPRM1OPRD1OPRK1OPRL1 | |
| Hydrochloric Acid SCHEMBL20791409 | 0.80 | SLC6A4 (0.41) | GBA1OPRM1OPRD1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4215529-A1 | HETEROARYL DERIVATIVE, METHOD FOR PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT | Voronoibio Inc. (KR) | 2023-07-26 | — | — | EP | disclosed |
| EP-3943491-A1 | HETEROARYL DERIVATIVE, METHOD FOR PRODUCING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS EFFECTIVE COMPONENT | Voronoi Inc. (KR) | 2022-01-26 | — | — | EP | disclosed |
| EP-1255738-B1 | GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO | NEUROCRINE BIOSCIENCES INC (US) | 2012-03-07 | — | — | EP | disclosed |