SCHEMBL1725802

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3094839	0.83	PTGES (0.44)	ROCK2KDM4EEHMT2DRD2TBXA2R
	SCHEMBL3098320	0.82	PTGES (0.52)	KDM4EHDAC6ALDH1A1NPC1MAPT
	SCHEMBL1725831	0.81	PTGES (0.61)	ROCK2KDM4EEHMT2KCNH2IDH1
	SCHEMBL3101603	0.80	PTGES (0.48)	KDM4EHDAC6KCNH2ALDH1A1LMNA
	SCHEMBL16318619	0.78	HDAC6 (0.51)	ROCK2KDM4EEHMT2ITKHDAC6
	SCHEMBL1974190	0.77	HDAC6 (0.47)	ROCK2KDM4EEHMT2ITKHDAC6
	SCHEMBL19029395	0.73	KDM4E (0.56)	KDM4EEHMT2HDAC6DRD2TBXA2R
	SCHEMBL1965112	0.72	HDAC6 (0.49)	KDM4EEHMT2HDAC6NPC1LMNA
	SCHEMBL30897550	0.71	KDM4E (0.56)	ROCK2KDM4EEHMT2ITKHDAC6
	SCHEMBL11947887	0.71	KDM4E (0.56)	ROCK2KDM4EEHMT2ITKHDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.