Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.73 |
| ▸ | TSHR | P16473 | 3/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.33 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22144196 | 1.00 | MEN1 (0.73) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL13625481 | 1.00 | MEN1 (0.73) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL12595181 | 1.00 | MEN1 (0.73) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL29861938 | 0.97 | MEN1 (0.69) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL168645 | 0.97 | — | — | |
| SCHEMBL8026479 | 0.93 | TSHR (0.67) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL1725816 | 0.93 | MEN1 (0.60) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL4422977 | 0.93 | MEN1 (0.60) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL1006922 | 0.91 | MEN1 (0.61) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL20534626 | 0.90 | TSHR (0.62) | MEN1KMT2ATSHRMAPK1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10723717-B2 | Compounds and methods for the targeted degradation of rapidly accelerated fibrosarcoma polypeptides | ARVINAS OPERATIONS, INC. (US) | 2020-07-28 | — | — | US | disclosed |
| CN-108473484-A | Compounds useful as TRPM8 modulators | 赛诺米克斯公司 | 2018-08-31 | — | — | CN | disclosed |
| US-8757396-B2 | Composite membrane with coating comprising polyalkylene oxide and oxy-substituted phenyl compounds | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-06-24 | — | — | US | disclosed |
| US-20110284457-A1 | COMPOSITE MEMBRANE WITH COATING COMPRISING POLYALKYLENE OXIDE AND OXY-SUBSTITUTED PHENYL COMPOUNDS | DOW GLOBAL TECHNOLOGIES LLC | 2011-11-24 | — | — | US | disclosed |
| EP-2349592-A2 | AUTOMOTIVE COATING SURFACE ENHANCEMENT USING A PLASMA TREATMENT TECHNIQUE | BASF Coatings GmbH (DE) | 2011-08-03 | — | — | EP | disclosed |
| US-20100104769-A1 | AUTOMOTIVE COATING SURFACE ENHANCEMENT USING A PLASMA TREATMENT TECHNIQUE | BASF CORPORATION | 2010-04-29 | — | — | US | disclosed |
| WO-2010048367-A2 | AUTOMOTIVE COATING SURFACE ENHANCEMENT USING A PLASMA TREATMENT TECHNIQUE | BASF CORPORATION (US) | 2010-04-29 | — | — | WO | disclosed |
| WO-2009136352-A1 | ANTI-ANGIOGENIC COMPOUNDS | COVX TECHNOLOGIES IRELAND, LTD. (IE) | 2009-11-12 | — | — | WO | disclosed |
| EP-1999196-A1 | COATINGS FOR POLYCARBONATE WINDOWS | BASF CORPORATION (US) | 2008-12-10 | — | — | EP | disclosed |
| EP-1482805-B1 | FOODSTUFF WRAPPING HAVING A ROUGH AND NATURALLY APPEARING SURFACE | KALLE GMBH (DE) | 2008-02-20 | — | — | EP | disclosed |
| WO-2003073861-A1 | WATER-VAPOUR AND SMOKE PERMEABLE FOOD CASING COMPRISING A ROUGH, NATURAL SURFACE | KALLE GMBH & CO. KG (DE) | 2003-09-12 | — | — | WO | disclosed |
| US-6331577-B1 | Process for producing elastic polyurethane moldings with compact surfaces and cellular cores | BASF AKTIENGESELLSCHAFT (DE) | 2001-12-18 | — | — | US | disclosed |
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |
| US-4581387-A | REACTION PRODUCT OF MONTANIC ACID AND TEN OR MORE CARBON ATOMS CARBOXYLIC ACID AND POLYOL, ALKANOLAMINE, OR POLYAMINE | BASF AKTIENGESELLSCHAFT (DE) | 1986-04-08 | — | — | US | disclosed |
| EP-0051818-B1 | PROCESS FOR THE PRODUCTION OF DISCHARGE-RESIST PRINTS ON TEXTILE MATERIALS | CASSELLA Aktiengesellschaft (DE) | 1985-09-04 | — | — | EP | disclosed |
| US-4398913-A | ALKALINE PASTES | CASSELLA AKTIENGESELLSCHAFT (DE) | 1983-08-16 | — | — | US | disclosed |
| US-4386935-A | Process for producing discharge reserve prints on textile materials with amino-azo-benzene dyes | CASSELLA AKTIENGESELLSCHAFT (DE) | 1983-06-07 | — | — | US | disclosed |
| EP-0051818-A1 | Process for the production of discharge-resist prints on textile materials | CASSELLA Aktiengesellschaft (DE) | 1982-05-19 | — | — | EP | disclosed |
| US-3993467-A | Hydroxyalkyl esters of N-phosphonomethyl glycine and the herbicidal use thereof | MONSANTO COMPANY (US) | 1976-11-23 | — | — | US | disclosed |
| US-3948975-A | CONTACT HERBICIDE | MONSANTO COMPANY (US) | 1976-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10723717-B2 | Compounds and methods for the targeted degradation of rapidly accelerated fibrosarcoma polypeptides | CRBN, ARAF, VHL | MEN1 2317/4885KMT2A 1975/4885TSHR 2304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.