⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL938084 | 0.60 | — | — | |
| SCHEMBL6509318 | 0.56 | — | — | |
| SCHEMBL7598017 | 0.51 | — | — | |
| SCHEMBL3660630 | 0.47 | TAAR1 (0.48) | — | |
| SCHEMBL9628046 | 0.47 | MAPT (0.68) | — | |
| Isopropylbenzene SCHEMBL3497916 | 0.47 | RIPK1 (0.42) | — | |
| SCHEMBL25333763 | 0.46 | HDAC4 (0.32) | — | |
| SCHEMBL17086696 | 0.46 | SLC6A4 (0.42) | — | |
| SCHEMBL15087920 | 0.46 | SLC6A4 (0.42) | — | |
| SCHEMBL1911313 | 0.46 | SLC6A4 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10344042-B2 | Production method for 2-fluoro-4-borono-L-phenylalanine, and precursor of 2-fluoro-4-borono-L-phenylalanine | STELLA PHARMA CORPORATION (JP) | 2019-07-09 | — | — | US | claimed |
| US-20170283441-A1 | PRODUCTION METHOD FOR 2-FLUORO-4-BORONO-L-PHENYLALANINE, AND PRECURSOR OF 2-FLUORO-4-BORONO-L-PHENYLALANINE | STELLA PHARMA CORPORATION (JP) | 2017-10-05 | — | — | US | claimed |
| US-10344042-B2 | Production method for 2-fluoro-4-borono-L-phenylalanine, and precursor of 2-fluoro-4-borono-L-phenylalanine | STELLA PHARMA CORPORATION (JP) | 2019-07-09 | — | — | US | disclosed |
| US-10005794-B2 | Production method for 2-fluoro-4-borono-L-phenylalanine, and precursor of 2-fluoro-4-borono-L-phenylalanine | STELLA PHARMA CORPORATION (JP) | 2018-06-26 | — | — | US | disclosed |
| US-9815855-B2 | Method for producing 4-borono-L-phenylalanine having 18F atom introduced thereinto, and precursor of 4-borono-L-phenylalanine having 18F atom introduced thereinto | STELLA PHARMA CORPORATION (JP) | 2017-11-14 | — | — | US | disclosed |
| US-20170283441-A1 | PRODUCTION METHOD FOR 2-FLUORO-4-BORONO-L-PHENYLALANINE, AND PRECURSOR OF 2-FLUORO-4-BORONO-L-PHENYLALANINE | STELLA PHARMA CORPORATION (JP) | 2017-10-05 | — | — | US | disclosed |
| US-20160311836-A1 | PRODUCTION METHOD FOR 2-FLUORO-4-BORONO-L-PHENYLALANINE, AND PRECURSOR OF 2-FLUORO-4-BORONO-L-PHENYLALANINE | STELLA PHARMA CORPORATION (JP) | 2016-10-27 | — | — | US | disclosed |
| US-9409926-B2 | Chiral 4-boronophenylalanine (BPA) derivative and method for producing same, and method for producing 18F-labeled BPA using said derivative | STELLA PHARMA CORPORATION; OSAKA PREFECTURE UNIVERSITY PUBLIC CORPORATION (JP) | 2016-08-09 | — | — | US | disclosed |
| US-20150329564-A1 | CHIRAL 4-BORONOPHENYLALANINE (BPA) DERIVATIVE AND METHOD FOR PRODUCING SAME, AND METHOD FOR PRODUCING 18F-LABELED BPA USING SAID DERIVATIVE | OSAKA PREFECTURE UNIVERSITY PUBLIC CORPORATION (JP) | 2015-11-19 | — | — | US | disclosed |