⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6509318 | 0.64 | — | — | |
| SCHEMBL17258254 | 0.60 | — | — | |
| SCHEMBL27333261 | 0.57 | MAOA (0.31) | — | |
| SCHEMBL25333763 | 0.48 | HDAC4 (0.32) | — | |
| SCHEMBL15275536 | 0.47 | GABRA1 (0.41) | — | |
| SCHEMBL301240 | 0.47 | CYP3A4 (0.45) | — | |
| SCHEMBL9092938 | 0.47 | KDM1A (0.37) | — | |
| Biphenyl SCHEMBL28308582 | 0.46 | ALDH1A1 (0.60) | — | |
| SCHEMBL10794005 | 0.46 | CYP3A4 (0.57) | — | |
| SCHEMBL3660630 | 0.46 | TAAR1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115806568-A | Method for constructing heteroatom substituted xanthene derivative through palladium-catalyzed cross coupling and application | 华东师范大学 | 2023-03-17 | — | — | CN | claimed |
| CN-115806562-A | Method for constructing boron-substituted xanthene dye through palladium-catalyzed cross coupling and application | 华东师范大学 | 2023-03-17 | — | — | CN | claimed |
| CN-114044769-A | Beta-indole quinazolinone derivative and preparation method and application thereof | 中山大学 | 2022-02-15 | — | — | CN | claimed |
| CN-111574567-A | Rigid heterocyclic compound, preparation method and application thereof, phosphine-containing sulfonamide compound and preparation method thereof | 中山大学 | 2020-08-25 | — | — | CN | claimed |
| US-20250320195-A1 | TETRAHYDRONAPHTHALENE AND TETRAHYDROISOQUINOLINE DERIVATIVES AS ESTROGEN RECEPTOR DEGRADERS | ARVINAS OPERATIONS INC (US) | 2025-10-16 | — | — | US | disclosed |
| US-12391663-B2 | Isoindolinone compounds | MONTE ROSA THERAPEUTICS AG (CH) | 2025-08-19 | — | — | US | disclosed |
| EP-4595965-A2 | HETEROALKYL DIHYDROQUINOLINE SULFONAMIDE COMPOUNDS | Amgen Inc. (US) | 2025-08-06 | — | — | EP | disclosed |
| US-12365686-B2 | Compound as porcupine inhibitor and use thereof | JIANGSU KANION PHARMACEUTICAL CO., LTD. (CN) | 2025-07-22 | — | — | US | disclosed |
| EP-4165032-B1 | HETEROALKYL DIHYDROQUINOLINE SULFONAMIDE COMPOUNDS | AMGEN INC (US) | 2025-04-16 | — | — | EP | disclosed |
| US-20250115581-A1 | SUBSTITUTED PIPERIDINES AS CK1A DEGRADERS | MONTE ROSA THERAPEUTICS AG (CH) | 2025-04-10 | — | — | US | disclosed |
| WO-2025067239-A1 | KINESIN KIF18A INHIBITOR, AND APPLICATION THEREOF | 上海湃隆生物科技有限公司 | 2025-04-03 | — | — | WO | disclosed |
| WO-2025067461-A1 | HETEROARYL DERIVATIVE AND USE THEREOF | 南京明德新药研发有限公司 | 2025-04-03 | — | — | WO | disclosed |
| WO-2013044092-A1 | AMINO-OXAZINES AND AMINO-DIHYDROTHIAZINE COMPOUNDS AS BETA-SECRETASE MODULATORS AND METHODS OF USE | AMGEN INC. (US) | 2013-03-28 | — | — | WO | disclosed |
| US-20120322784-A1 | Compounds, pharmaceutical compositions and uses thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-12-20 | — | — | US | disclosed |
| EP-2212332-B1 | SUBSTITUTED TRICYCLIC COMPOUNDS AND METHODS OF USE THEREOF | BAYER IP GMBH (DE) | 2012-10-24 | — | — | EP | disclosed |
| WO-2012080476-A1 | FUSED DIHYDROPYRANS AS GPR119 MODULATORS FOR THE TREATMENT OF DIABETES, OBESITY AND RELATED DISEASES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-21 | — | — | WO | disclosed |
| US-20110021493-A1 | SUBSTITUTED TRICYCLIC COMPOUNDS AND METHODS OF USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2011-01-27 | — | — | US | disclosed |
| EP-2212332-A1 | SUBSTITUTED TRICYCLIC COMPOUNDS AND METHODS OF USE THEREOF | Bayer Schering Pharma Aktiengesellschaft (DE) | 2010-08-04 | — | — | EP | disclosed |
| WO-2010081851-A1 | PIPERIDIN-4-YLPIPERAZINE COMPOUNDS FOR THE TREATMENT OF HCV INFECTION | GENOSCIENCE PHARMA (FR) | 2010-07-22 | — | — | WO | disclosed |
| WO-2009033581-A1 | SUBSTITUTED TRICYCLIC COMPOUNDS AND METHODS OF USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-03-19 | — | — | WO | disclosed |