Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.50 |
| ▸ | FABP3 | P05413 | 1/20 | 0.48 |
| ▸ | FABP4 | P15090 | 1/20 | 0.48 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7475795 | 0.87 | HTT (0.57) | MYCHTTGPR35FABP3FABP4 | |
| SCHEMBL17744822 | 0.87 | MMP2 (0.57) | MYCALDH1A1KDM4EHSD17B10KMT2A | |
| SCHEMBL15517040 | 0.84 | GPR35 (0.57) | MYCHTTGPR35FABP3FABP4 | |
| SCHEMBL14675659 | 0.83 | HTT (0.53) | MYCHTTGPR35FABP3FABP4 | |
| SCHEMBL10527823 | 0.83 | MYC (0.57) | MYCALDH1A1KDM4EHSD17B10KMT2A | |
| SCHEMBL28370924 | 0.82 | MYC (0.61) | MYCHTTGPR35FABP3FABP4 | |
| SCHEMBL17744779 | 0.82 | MMP2 (0.55) | MYCALDH1A1KDM4EHSD17B10KMT2A | |
| SCHEMBL17258267 | 0.81 | HTT (0.54) | MYCHTTGPR35FABP3FABP4 | |
| 1,2-Dimethoxybenzene SCHEMBL28306871 | 0.80 | HTT (0.66) | HTTFABP3FABP4FABP5ALDH1A1 | |
| SCHEMBL3824307 | 0.80 | MYC (0.67) | MYCFABP4ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150328329-A1 | LIGANDS THAT TARGET HCV-E2 BINDING SITES ON CD81 AND THERAPEUTIC METHODS USING THEM | American University of Cairo (EG) | 2015-11-19 | — | — | US | disclosed |