Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.31 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17263010 | 0.86 | TDP1 (0.40) | AOC3NPSR1HRH4GRIN2DGRIN3B | |
| SCHEMBL17258393 | 0.83 | HDAC1 (0.36) | NPSR1MEN1KMT2A | |
| SCHEMBL17258343 | 0.80 | MEP1B (0.41) | MEN1KMT2ANPC1RAB9A | |
| SCHEMBL17258450 | 0.80 | PTGER2 (0.35) | MEN1KMT2A | |
| SCHEMBL20442121 | 0.80 | KDM4E (0.40) | NPSR1KMT2AHRH4HDAC8HSD17B10 | |
| SCHEMBL20416907 | 0.78 | MEN1 (0.35) | MEN1KMT2A | |
| SCHEMBL20416576 | 0.74 | MRGPRX4 (0.45) | NPC1RAB9A | |
| SCHEMBL20416580 | 0.73 | MEN1 (0.42) | NPSR1MEN1KMT2AHRH4GRIN2D | |
| SCHEMBL15259719 | 0.73 | HRH4 (0.47) | NPSR1HRH4GRIN2DGRIN3BGRIN1 | |
| SCHEMBL20416590 | 0.73 | ALOX15 (0.33) | NPSR1MEN1KMT2AHDAC8ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9469656-B2 | HDAC inhibitors as anti-cancer agents | THE UNIVERSITY OF TOLEDO (US) | 2016-10-18 | — | — | US | disclosed |
| US-20150329560-A1 | HDAC Inhibitors as Anti-Cancer Agents | THE UNIVERSITY OF TOLEDO (US) | 2015-11-19 | — | — | US | disclosed |
| US-8999321-B2 | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glycyl-tRNA synthetases | ATYR PHARMA, INC. (US) | 2015-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150329560-A1 | HDAC Inhibitors as Anti-Cancer Agents | HDAC1, HDAC4, HDAC5 | AOC3 3252/4885NPSR1 4535/4885PDE7B 741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.