Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.38 |
| ▸ | GRK5 | P34947 | 1/20 | 0.38 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1725765 | 0.94 | CHEK1 (0.42) | CHEK1DAPK3GRK5LIMK1MAPT | |
| SCHEMBL170898 | 0.76 | PDE10A (0.34) | MAPTL3MBTL1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL1727361 | 0.76 | CYP1A2 (0.32) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL170955 | 0.73 | POLB (0.35) | CYP1A2CYP3A4CYP2C9CYP2C19POLB | |
| SCHEMBL1724939 | 0.67 | PDE10A (0.41) | MAPTSMN1; SMN2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL1724913 | 0.66 | PDE2A (0.41) | LMNACYP1A2POLB | |
| SCHEMBL22143978 | 0.65 | MAPT (0.48) | CHEK1DAPK3GRK5LIMK1MAPT | |
| SCHEMBL27212602 | 0.63 | PKM (0.47) | CHEK1DAPK3GRK5LIMK1MAPT | |
| SCHEMBL13106292 | 0.63 | CHEK1 (0.51) | CHEK1DAPK3GRK5LIMK1MAPT | |
| SCHEMBL10751685 | 0.61 | CHEK1 (0.49) | CHEK1DAPK3GRK5LIMK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403834-A1 | Fungicidal pyrazoles | E. I. du Pont de Nemours and Company (US) | 2012-01-11 | — | — | EP | disclosed |
| WO-2010101973-A1 | FUNGICIDAL PYRAZOLES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-09-10 | — | — | WO | disclosed |