Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | TYR | P14679 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.41 |
| ▸ | ESR1 | P03372 | 3/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14037093 | 0.91 | CA1 (0.43) | CA1CA2TYRHTTNPC1 | |
| SCHEMBL5140860 | 0.90 | TYR (0.50) | TYRHTTNPC1HPGDMAPK1 | |
| SCHEMBL2525138 | 0.87 | ALOX5 (0.50) | CA1CA2TYRHTTALOX5 | |
| SCHEMBL1022203 | 0.84 | ESR1 (0.41) | CA1CA2TYRESR1MAOA | |
| SCHEMBL13895963 | 0.84 | TYR (0.46) | TYRHTTNPC1HPGDMAPK1 | |
| SCHEMBL11612512 | 0.82 | CA1 (0.54) | CA1CA2HTTALOX5ESR1 | |
| SCHEMBL1022719 | 0.80 | TYR (0.44) | TYRHTTALOX5ESR1PTGS2 | |
| SCHEMBL280118 | 0.79 | TYR (0.48) | TYRHTTNPC1HPGDMAPK1 | |
| SCHEMBL12457001 | 0.79 | TYR (0.46) | TYRHTTALOX5PTGS2EGFR | |
| SCHEMBL1021056 | 0.79 | TYR (0.46) | TYRHTTALOX5PTGS2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1521125-B1 | Electrophotographic photoconductor, electrophotographic method, electrophotographic apparatus, process cartridge for electrophotographic apparatus and azo compound | RICOH CO LTD (JP) | 2012-03-07 | — | — | EP | disclosed |
| US-7556902-B2 | Aromatic polyester resin, and electrophotographic photoconductor and image forming apparatus using thereof | RICOH COMPANY, LTD. (JP) | 2009-07-07 | — | — | US | disclosed |