SCHEMBL5140860

SCHEMBL5140860

CCCCc1cc(-c2cc(CCCC)c(O)c(CCCC)c2)cc(CCCC)c1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 3/20 0.50
ALOX5 P09917 6/20 0.47
PTGS2 P35354 7/20 0.46
EGFR P00533 1/20 0.45
HTT P42858 2/20 0.43
MAPK1 P28482 2/20 0.43
NPC1 O15118 1/20 0.43
HPGD P15428 1/20 0.43
RAB9A P51151 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
CYP3A4 P08684 2/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
TP53 P04637 1/20 0.42
MAPT P10636 1/20 0.42
ALOX15 P16050 1/20 0.42
TSHR P16473 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
MAOA P21397 1/20 0.39
AKR1C2 P52895 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13895963 0.94 TYR (0.46) TYRALOX5PTGS2EGFRHTT
SCHEMBL172598 0.90 CA1 (0.54) TYRALOX5PTGS2EGFRHTT
SCHEMBL12457001 0.88 TYR (0.46) TYRALOX5PTGS2EGFRHTT
SCHEMBL1760464 0.86 ALOX5 (0.61) TYRALOX5PTGS2EGFRHTT
SCHEMBL10407157 0.86 PTGS2 (0.51) TYRALOX5PTGS2HTTCYP3A4
SCHEMBL8975468 0.85 ALOX5 (0.44) ALOX5PTGS2
SCHEMBL14037093 0.85 CA1 (0.43) TYRALOX5PTGS2EGFRHTT
SCHEMBL1023197 0.85 TYR (0.43) TYRALOX5PTGS2EGFRHTT
SCHEMBL280118 0.84 TYR (0.48) TYRALOX5PTGS2EGFRHTT
SCHEMBL201692 0.84 NPC1 (0.57) TYRALOX5PTGS2EGFRHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8007426-B2 Developing roller KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2011-08-30 US disclosed
US-20110177338-A1 CARBON BLACK KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2011-07-21 US disclosed
US-7951310-B2 Nanophase carbon black grafted with organic compound in situ EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2011-05-31 US disclosed
US-20100119437-A1 METHOD FOR PRODUCING CARBON BLACK KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2010-05-13 US disclosed
US-20100004333-A1 COMPOSITIONS AND METHODS FOR TREATING CARDIOVASCULAR DISORDERS STOCKER ROLAND O 2010-01-07 US disclosed
US-20090226722-A1 CARBON BLACK UHIDA MASAFUMI 2009-09-10 US disclosed
US-20090214865-A1 CARBON BLACK KONICA MINOLTA BUSHINESS TECHNOLOGIES INC. (JP) 2009-08-27 US disclosed
US-20090087766-A1 TONER FOR DEVELOPING ELECTROSTATIC LATENT IMAGE KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2009-04-02 US disclosed
US-20090035027-A1 DEVELOPING ROLLER KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2009-02-05 US disclosed
US-7466326-B2 Image forming method and image forming apparatus KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2008-12-16 US disclosed
EP-1521806-A1 THERMOPLASTIC POLYCARBONATE COMPOSITIONS HAVING HIGH TOUGHNESS Bayer MaterialScience LLC (US) 2005-04-13 EP disclosed
US-20040186233-A1 Molding composition containing (CO)polycarbonates BAYER MATERIALSCIENCE AG (DE) 2004-09-23 US disclosed
US-6753405-B2 MORE THAN 35 MOLE % OF UNITS DERIVED FROM DIHYDROXYDIPHENYLENE AND THE REST FROM AN ALKYLIDENE OR CYCLOALKYLIDENE BISPHENOL; PREPARED BY MELT TRANSESTERIFICATION; USED TO PREPARE TRANSPARENT MOLDINGS BAYER AKTIENGESELLSCHAFT (DE) 2004-06-22 US disclosed
US-6740714-B2 RESISTANCE TO STRESS CRACKING AND GOOD LOW- TEMPERATURE PROPERTIES IS SUITABLE FOR AUTOMOTIVE CONSTRUCTION AND EXTERIOR APPLICATIONS; MOLDING MATERIALS BAYER AKTIENGESELLSCHAFT (DE) 2004-05-25 US disclosed
US-6730748-B2 HIGH IMPACT STRENGTH; COLD RESISTANCE; 4,4*-DIHYDROXYBIPHENYL DERIVATIVE MONOMERS BAYER POLYMERS LLC 2004-05-04 US disclosed
WO-2004005401-A1 THERMOPLASTIC POLYCARBONATE COMPOSITIONS HAVING HIGH TOUGHNESS BAYER MATERIALSCIENCE LLC (US) 2004-01-15 WO disclosed
US-20040010097-A1 Thermoplastic polycarbonate compositions having high toughness BAYER CORPORATION 2004-01-15 US disclosed
US-20030040586-A1 Polycarbonate blends COVESTRO DEUTSCHLAND AG (DE) 2003-02-27 US disclosed
US-20030027971-A1 Preparation of copolycarbonates BAYER AKTIENGESELLSCHAFT (DE) 2003-02-06 US disclosed
US-5098965-A Etherification of biphenol with epichlorohydrin by dehydrochlorination SHELL OIL COMPANY (US) 1992-03-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100004333-A1 COMPOSITIONS AND METHODS FOR TREATING CARDIOVASCULAR DISORDERS SCLY, SELENOI, CBS TYR 147/4885ALOX5 235/4885PTGS2 549/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.