Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ELANE | P08246 | 2/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13320901 | 0.85 | MAPT (0.44) | MAPTSIRT3TDP1KDM4ESMN1; SMN2 | |
| SCHEMBL29955774 | 0.83 | KDM4C (0.48) | MAPTSIRT3TDP1KDM4EKMT2A | |
| SCHEMBL4619119 | 0.83 | KDM4C (0.48) | MAPTSIRT3TDP1KDM4EKMT2A | |
| SCHEMBL30874483 | 0.81 | SIRT3 (0.55) | MAPTSIRT3TDP1KDM4EKMT2A | |
| SCHEMBL25085773 | 0.81 | ALDH1A1 (0.54) | TDP1KDM4ESMN1; SMN2KMT2AHTT | |
| SCHEMBL17257170 | 0.78 | SIRT3 (0.37) | MAPTSIRT3TDP1KDM4EKMT2A | |
| SCHEMBL17257171 | 0.78 | SIRT3 (0.37) | MAPTSIRT3TDP1KDM4EKMT2A | |
| SCHEMBL28317597 | 0.76 | TDP1 (0.50) | MAPTSIRT3TDP1KDM4ESMN1; SMN2 | |
| SCHEMBL17256872 | 0.75 | HTT (0.35) | SIRT3TDP1KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL20384869 | 0.75 | HTT (0.35) | SIRT3TDP1KDM4ESMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3143055-A2 | POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS CONTAINING A CYANO GROUP | Bridgestone Corporation (JP) | 2017-03-22 | — | — | EP | claimed |
| WO-2015175280-A2 | POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS CONTAINING A CYANO GROUP | BRIDGESTONE CORPORATION (JP) | 2015-11-19 | — | — | WO | claimed |