Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.72 |
| ▸ | POLB | P06746 | 1/20 | 0.72 |
| ▸ | TSHR | P16473 | 7/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | CDC25B | P30305 | 2/20 | 0.52 |
| ▸ | KDM4A | O75164 | 1/20 | 0.52 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | MMP12 | P39900 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22532123 | 0.87 | ALDH1A1 (0.68) | ALDH1A1KDM4EHSD17B10POLBTSHR | |
| SCHEMBL11855194 | 0.87 | ALDH1A1 (0.73) | ALDH1A1KDM4EHSD17B10POLBTSHR | |
| SCHEMBL11859849 | 0.87 | ALDH1A1 (0.73) | ALDH1A1KDM4EHSD17B10POLBTSHR | |
| SCHEMBL13360008 | 0.86 | TSHR (0.77) | ALDH1A1KDM4EHSD17B10POLBTSHR | |
| SCHEMBL3102580 | 0.85 | ALDH1A1 (0.97) | ALDH1A1KDM4EHSD17B10POLBTSHR | |
| SCHEMBL7147146 | 0.84 | ALDH1A1 (0.78) | ALDH1A1KDM4EHSD17B10POLBTSHR | |
| SCHEMBL7145292 | 0.84 | ALDH1A1 (0.78) | ALDH1A1KDM4EHSD17B10POLBTSHR | |
| SCHEMBL7542400 | 0.84 | ALDH1A1 (1.00) | ALDH1A1KDM4EHSD17B10POLBTSHR | |
| SCHEMBL873445 | 0.84 | ALDH1A1 (1.00) | ALDH1A1KDM4EHSD17B10POLBTSHR | |
| SCHEMBL7538114 | 0.84 | ALDH1A1 (1.00) | ALDH1A1KDM4EHSD17B10POLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3143185-B1 | METHOD FOR THE ELECTROCHEMICAL AMINATION AT BORON DOPED DIAMOND ANODES | COVESTRO DEUTSCHLAND AG (DE) | 2018-10-03 | — | — | EP | disclosed |
| EP-3143185-A1 | METHOD FOR PRODUCING 1.5-DIAMINONAPHTHALENE AND 1-AMINO-5-NITRONAPHTHALENE BY DIRECT ELECTROCHEMICAL AMINATION OF NON-ACTIVATED OR DEACTIVATED AROMATIC SYSTEMS ON BORON-DOPED DIAMOND ANODES | Covestro Deutschland AG (DE) | 2017-03-22 | — | — | EP | disclosed |
| WO-2015173221-A1 | METHOD FOR PRODUCING 1.5-DIAMINONAPHTHALENE AND 1-AMINO-5-NITRONAPHTHALENE BY DIRECT ELECTROCHEMICAL AMINATION OF NON-ACTIVATED OR DEACTIVATED AROMATIC SYSTEMS ON BORON-DOPED DIAMOND ANODES | COVESTRO DEUTSCHLAND AG (DE) | 2015-11-19 | — | — | WO | disclosed |