Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.88 |
| ▸ | CES2 | O00748 | 2/20 | 0.45 |
| ▸ | CES1 | P23141 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.43 |
| ▸ | FFAR3 | O14843 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | DGKA | P23743 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | BCL9 | O00512 | 1/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28189866 | 0.97 | ALDH1A1 (0.94) | ALDH1A1CES2CES1HDAC3HDAC1 | |
| SCHEMBL5144632 | 0.97 | ALDH1A1 (0.94) | ALDH1A1CES2CES1HDAC3HDAC1 | |
| SCHEMBL9556715 | 0.97 | ALDH1A1 (0.94) | ALDH1A1CES2CES1HDAC3HDAC1 | |
| SCHEMBL8158 | 0.94 | ALDH1A1 (1.00) | ALDH1A1CES2CES1HDAC3HDAC1 | |
| SCHEMBL30568759 | 0.94 | ALDH1A1 (1.00) | ALDH1A1CES2CES1HDAC3HDAC1 | |
| SCHEMBL10425674 | 0.92 | ALDH1A1 (0.83) | ALDH1A1CES2CES1HDAC3HDAC1 | |
| SCHEMBL27743311 | 0.91 | ALDH1A1 (0.94) | ALDH1A1CES2CES1HDAC3HDAC1 | |
| SCHEMBL10640242 | 0.91 | ALDH1A1 (0.94) | ALDH1A1CES2CES1HDAC3HDAC1 | |
| SCHEMBL28174826 | 0.91 | ALDH1A1 (0.94) | ALDH1A1CES2CES1HDAC3HDAC1 | |
| SCHEMBL17477083 | 0.91 | ALDH1A1 (0.94) | ALDH1A1CES2CES1HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12622885-B2 | Short chain fatty acid compounds and uses thereof | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2026-05-12 | — | — | US | disclosed |
| US-20250268851-A1 | SHORT CHAIN FATTY ACID COMPOUNDS AND USES THEREOF | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2025-08-28 | — | — | US | disclosed |
| WO-2025137671-A1 | SHORT CHAIN FATTY ACID COMPOUNDS AND USES THEREOF | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2025-06-26 | — | — | WO | disclosed |
| US-11141391-B2 | Biomarkers for risk assessment, diagnosis and target microbiome and intestinal homeostasis for prevention and treatment of amyotrophic lateral sclerosis | RUSH UNIVERSITY MEDICAL CENTER (US) | 2021-10-12 | — | — | US | disclosed |
| CN-107494980-A | One hatching egg feed additive for fowls and its application | 盐城六和饲料有限公司 | 2017-12-22 | — | — | CN | disclosed |
| US-20170296494-A1 | Biomarkers for Risk Assessment, Diagnosis and Target Microbiome and Intestinal Homeostasis for Prevention and Treatment of Amyotrophic Lateral Sclerosis | RUSH UNIVERSITY MEDICAL CENTER (US) | 2017-10-19 | — | — | US | disclosed |
| CN-106107192-A | A kind of egg fowl feed additive and application thereof | 杭州康德权饲料有限公司 | 2016-11-16 | — | — | CN | disclosed |
| WO-2015175388-A1 | BIOMARKERS FOR RISK ASSESSMENT, DIAGNOSIS AND TARGET MICROBIOME AND INTESTINAL HOMEOSTASIS FOR PREVENTION AND TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS | RUSH UNIVERSITY MEDICAL CENTER (US) | 2015-11-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12622885-B2 | Short chain fatty acid compounds and uses thereof | HRH1, H1-0, HLA-DRB1 | ALDH1A1 385/4885CES2 2040/4885CES1 90/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.