Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.35 |
| ▸ | PARP1 | P09874 | 2/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SOD1 | P00441 | 1/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30947236 | 0.76 | HTT (0.38) | MAP3K14HTTALDH1A1HSD17B10TDP1 | |
| SCHEMBL21382485 | 0.76 | HTT (0.38) | MAP3K14HTTALDH1A1HSD17B10TDP1 | |
| SCHEMBL15601923 | 0.74 | HTT (0.56) | HTTALDH1A1NOTUMSMN1; SMN2SOD1 | |
| SCHEMBL16285368 | 0.72 | HTT (0.46) | HTTTDP1NOTUMGPR119GRM1 | |
| SCHEMBL12594227 | 0.70 | NOS3 (0.45) | NOS3NOS1NOS2ALDH1A1HSD17B10 | |
| SCHEMBL13390916 | 0.68 | GAA (0.45) | NOS3NOS1NOS2HTTALDH1A1 | |
| SCHEMBL21382262 | 0.67 | EGLN2 (0.41) | HTTALDH1A1GPR119 | |
| SCHEMBL21348667 | 0.66 | NOS3 (0.41) | NOS3NOS1NOS2LOXL2MAP3K14 | |
| SCHEMBL10274925 | 0.66 | HRH4 (0.51) | NOS3NOS1NOS2LOXL2ALDH1A1 | |
| SCHEMBL8721375 | 0.66 | RPS6KA5 (0.41) | HTTALDH1A1HSD17B10TDP1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160289191-A1 | ORGANIC COMPOUNDS | XENON PHARMACEUTICALS INC. (CA) | 2016-10-06 | — | — | US | disclosed |
| US-9187426-B2 | Organic compounds | NOVARTIS AG (CH) | 2015-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160289191-A1 | ORGANIC COMPOUNDS | SCD, SCD5, FADS2 | NOS3 912/4885NOS1 1344/4885NOS2 1158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.