SCHEMBL17263265

SCHEMBL17263265

CCc1nccnc1-c1cc2ccccc2cc1C

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 1/20 0.37
CCR8 P51685 1/20 0.37
HEXA P06865 1/20 0.35
HEXB P07686 1/20 0.35
CYP1A2 P05177 2/20 0.34
CYP2A6 P11509 2/20 0.34
CYP11B1 P15538 2/20 0.33
CYP11B2 P19099 2/20 0.33
PDE10A Q9Y233 2/20 0.33
MBNL1 Q9NR56 1/20 0.33
KDM4E B2RXH2 1/20 0.33
NPC1 O15118 1/20 0.33
PDK1 Q15118 1/20 0.32
GLA P06280 2/20 0.32
REN P00797 1/20 0.32
ATM Q13315 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
PIK3CD O00329 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17263277 0.80 CYP2A6 (0.41) CCR1CCR8CYP1A2CYP2A6CYP11B1
SCHEMBL17263269 0.77 CYP1A2 (0.39) HEXAHEXBCYP1A2PDK1
SCHEMBL17263268 0.77 PDK1 (0.37) KDM4EPDK1GLA
SCHEMBL11996934 0.76 KMT2A (0.36) HEXAHEXBCYP1A2KDM4E
SCHEMBL17263267 0.75 CYP1A2 (0.35) CYP1A2
SCHEMBL10000613 0.73 CHEK1 (0.36) CCR1CCR8CYP1A2CYP2A6CYP11B1
SCHEMBL10000615 0.72 MYC (0.38) CCR1CCR8PDE10AKDM4EATM
SCHEMBL31498513 0.71 ALDH1A1 (0.40) CYP1A2PDE10AMBNL1KDM4ENPC1
SCHEMBL16062611 0.70 CYP2A6 (0.48) CCR1CCR8CYP1A2CYP2A6CYP11B1
SCHEMBL14094485 0.70 PDK1 (0.44) HEXAHEXBKDM4EPDK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9187689-B2 Organometallic complex and light-emitting element, light-emitting device, and electronic device using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-11-17 US disclosed