SCHEMBL17263277

SCHEMBL17263277

Cc1cc2ccccc2cc1-c1nccnc1C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 3/20 0.41
CCR1 P32246 3/20 0.41
CCR8 P51685 3/20 0.41
CYP1A2 P05177 2/20 0.38
PDE10A Q9Y233 1/20 0.37
KDM4E B2RXH2 1/20 0.37
NPC1 O15118 1/20 0.37
MBNL1 Q9NR56 1/20 0.37
CYP11B1 P15538 2/20 0.36
CYP11B2 P19099 2/20 0.36
TDP1 Q9NUW8 2/20 0.35
ATM Q13315 1/20 0.35
ALDH1A1 P00352 2/20 0.33
DRD1 P21728 1/20 0.33
CCR5 P51681 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
NQO2 P16083 1/20 0.32
TP53 P04637 1/20 0.32
HPGD P15428 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17263265 0.80 CCR1 (0.37) CYP2A6CCR1CCR8CYP1A2PDE10A
SCHEMBL17263288 0.79 JAK3 (0.45) CYP2A6CCR1CCR8CYP1A2PDE10A
SCHEMBL10000613 0.78 CHEK1 (0.36) CYP2A6CCR1CCR8CYP1A2PDE10A
SCHEMBL10000615 0.77 MYC (0.38) CCR1CCR8PDE10AKDM4ETDP1
SCHEMBL16062611 0.75 CYP2A6 (0.48) CYP2A6CCR1CCR8CYP1A2PDE10A
SCHEMBL17691558 0.74 CYP2A6 (0.55) CYP2A6KDM4EALDH1A1HPGDHSD17B10
SCHEMBL16805042 0.74 ABL1 (0.49) CYP2A6CYP1A2KDM4ECYP11B1CYP11B2
SCHEMBL17263279 0.74 ESR2 (0.40) CYP2A6KDM4ENPC1ATMALDH1A1
SCHEMBL13320916 0.74 CYP1A2 (0.39) CYP2A6CYP1A2PDE10AKDM4ENPC1
SCHEMBL13863592 0.74 CYP3A4 (0.49) CYP2A6CCR1CCR8CYP1A2CYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9187689-B2 Organometallic complex and light-emitting element, light-emitting device, and electronic device using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-11-17 US disclosed