Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | CCR8 | P51685 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | MBNL1 | Q9NR56 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17263277 | 0.79 | CYP2A6 (0.41) | CYP1A2CYP2A6CYP11B1CYP11B2CCR1 | |
| SCHEMBL13320917 | 0.78 | JAK3 (0.48) | JAK3CYP1A2PDE10AKMT2ACCNB2 | |
| SCHEMBL17263290 | 0.78 | JAK3 (0.48) | JAK3PDE10AKMT2ACCNB2CDK1 | |
| SCHEMBL17263289 | 0.77 | JAK3 (0.46) | JAK3CCR1CCR8PDE10AKMT2A | |
| SCHEMBL3222556 | 0.76 | JAK3 (0.61) | JAK3CYP1A2CYP2A6CYP11B1CYP11B2 | |
| SCHEMBL1603653 | 0.76 | DHFR (0.44) | JAK3CYP2A6ALDH1A1MAPTKDM4E | |
| SCHEMBL14495843 | 0.75 | JAK3 (0.37) | JAK3KMT2APDK2 | |
| SCHEMBL2514027 | 0.73 | JAK3 (0.54) | JAK3CYP1A2CYP2A6CYP11B1CYP11B2 | |
| SCHEMBL16062611 | 0.72 | CYP2A6 (0.48) | CYP1A2CYP2A6CYP11B1CYP11B2CCR1 | |
| SCHEMBL3335530 | 0.72 | JAK3 (0.56) | JAK3CYP1A2PDE10AKMT2ACCNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9187689-B2 | Organometallic complex and light-emitting element, light-emitting device, and electronic device using the same | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2015-11-17 | — | — | US | disclosed |