Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 10/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1767525 | 0.91 | SCD (0.44) | SCDHDAC1KDM4EALDH1A1 | |
| SCHEMBL1568368 | 0.90 | SCD (0.54) | SCDHDAC1NAMPTROCK2MAPT | |
| SCHEMBL1767552 | 0.88 | HDAC1 (0.48) | SCDHDAC1NAMPTROCK2 | |
| SCHEMBL1767401 | 0.87 | SCD (0.45) | SCDNAMPTROCK2MAPTKDM4E | |
| SCHEMBL17263335 | 0.85 | SCD (0.42) | SCDHDAC1MAPTTHRB | |
| SCHEMBL17263334 | 0.85 | SCD (0.44) | SCDHDAC1MAPTTHRB | |
| SCHEMBL17263331 | 0.79 | SCD (0.44) | SCDHDAC1P2RX3ROCK2 | |
| SCHEMBL1767404 | 0.78 | SCD (0.51) | SCDHDAC1MAPTTHRB | |
| SCHEMBL1767386 | 0.78 | SCD (0.52) | SCDHDAC1ROCK2MAPTKDM4E | |
| SCHEMBL1767437 | 0.78 | SCD (0.53) | SCDHDAC1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9187426-B2 | Organic compounds | NOVARTIS AG (CH) | 2015-11-17 | — | — | US | disclosed |