Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 3/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GPR52 | Q9Y2T5 | 5/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1568275 | 0.88 | GPR52 (0.45) | SCDHDAC1ROCK2RAB9AGPR52 | |
| SCHEMBL1568774 | 0.87 | SCD (0.57) | SCDHDAC1ROCK2RAB9AOPRK1 | |
| SCHEMBL1568559 | 0.84 | HDAC1 (0.54) | SCDHDAC1ROCK2RAB9AGPR52 | |
| SCHEMBL1568208 | 0.83 | GPR52 (0.48) | SCDHDAC1ROCK2RAB9AGPR52 | |
| SCHEMBL17263335 | 0.80 | SCD (0.42) | SCDHDAC1 | |
| SCHEMBL17263334 | 0.80 | SCD (0.44) | SCDHDAC1 | |
| SCHEMBL17263326 | 0.79 | SCD (0.45) | SCDHDAC1ROCK2P2RX3 | |
| SCHEMBL1568058 | 0.78 | RAB9A (0.54) | SCDHDAC1RAB9A | |
| SCHEMBL1567882 | 0.76 | KDM5A (0.55) | SCDHDAC1RAB9A | |
| SCHEMBL1568707 | 0.75 | HDAC1 (0.55) | HDAC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9187426-B2 | Organic compounds | NOVARTIS AG (CH) | 2015-11-17 | — | — | US | disclosed |