Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 9/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
| ▸ | KLK1 | P06870 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16160216 | 0.91 | HDAC1 (0.48) | SCDHDAC1MAPTKLKB1KLK1 | |
| SCHEMBL1767462 | 0.91 | SCD (0.41) | SCDHDAC1KLKB1 | |
| SCHEMBL17263334 | 0.90 | SCD (0.44) | SCDHDAC1THRBMAPTKDM1A | |
| SCHEMBL1767688 | 0.90 | SCD (0.50) | SCDHDAC1MAPTKLKB1KLK1 | |
| SCHEMBL1767488 | 0.88 | HDAC1 (0.49) | SCDHDAC1KDM1A | |
| SCHEMBL1767539 | 0.87 | ROCK2 (0.42) | SCDHDAC1KLKB1TSHR | |
| SCHEMBL17263326 | 0.85 | SCD (0.45) | SCDHDAC1THRBMAPT | |
| SCHEMBL1767489 | 0.81 | SCD (0.43) | SCDHDAC1KLKB1 | |
| SCHEMBL1767515 | 0.80 | SCD (0.52) | SCDHDAC1MAPTKLKB1KLK1 | |
| SCHEMBL17263331 | 0.80 | SCD (0.44) | SCDHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9187426-B2 | Organic compounds | NOVARTIS AG (CH) | 2015-11-17 | — | — | US | disclosed |