⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27643705 | 0.98 | KMT2A (0.47) | — | |
| SCHEMBL23293397 | 0.80 | KMT2A (0.40) | — | |
| SCHEMBL21484937 | 0.80 | CDC7 (0.39) | — | |
| SCHEMBL28164379 | 0.79 | — | — | |
| SCHEMBL2650842 | 0.79 | — | — | |
| SCHEMBL6368963 | 0.79 | ALDH1A1 (0.42) | — | |
| SCHEMBL28296615 | 0.79 | KMT2A (0.41) | — | |
| SCHEMBL290564 | 0.79 | CDC7 (0.49) | — | |
| SCHEMBL5140577 | 0.79 | KMT2A (0.51) | — | |
| Methyl Alcohol SCHEMBL28357518 | 0.78 | KMT2A (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 189 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483440-A | A kind of preparation method of 2- (the bromo- 1,3- thiazole -5- base of 2-) acetonitrile | SHANGHAI RAISE CHEMICAL TECH CO LTD | 2019-11-22 | — | — | CN | claimed |
| US-10224485-B2 | Process for preparing a crystalline organic semiconductor material | BASF SE (DE) | 2019-03-05 | — | — | US | claimed |
| CN-106632134-A | 2-(4-thiazolinone-2-imino)thiazole-5-carboxylate and preparation method and application thereof | 湖南大学 | 2017-05-10 | — | — | CN | claimed |
| US-20170012208-A1 | ORGANIC SEMICONDUCTOR FORMULATIONS | USINVEST LLC | 2017-01-12 | — | — | US | claimed |
| CN-1185219-C | Trans olefinic glucokinase activators | HOFFMANN LA ROCHE (CH) | 2005-01-19 | — | — | CN | claimed |
| CN-1411453-A | Trans olefinic glucokinase activators | HOFFMANN LA ROCHE (CH) | 2003-04-16 | — | — | CN | claimed |
| WO-2026103337-A1 | NOVEL SUBSTITUTED HETEROCYCLIC COMPOUND AS APELIN RECEPTOR MODULATOR | 德睿智药(苏州)新药研发有限公司 | 2026-05-21 | — | — | WO | disclosed |
| EP-4665733-A1 | AMINO-SUBSTITUTED PYRROLOTRIAZINE DERIVATIVES AS INHIBITORS OF SGK1 | Bristol-Myers Squibb Company (US) | 2025-12-24 | — | — | EP | disclosed |
| CN-113072546-B | Five-membered heteroaromatic derivative and preparation method and application thereof | 广东东阳光药业股份有限公司 | 2025-05-30 | — | — | CN | disclosed |
| CN-119684317-A | Macrocyclic compound and application thereof | 郑州德迈药业有限公司 | 2025-03-25 | — | — | CN | disclosed |
| WO-2024173323-A1 | AMINO-SUBSTITUTED PYRROLOTRIAZINE DERIVATIVES AS INHIBITORS OF SGK1 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-08-22 | — | — | WO | disclosed |
| CN-118451078-A | Modified proteins and protein degrading agents | 上海睿跃生物科技有限公司 | 2024-08-06 | — | — | CN | disclosed |
| CN-112867712-B | Carboxamide as ubiquitin-specific protease inhibitor | 瓦洛早期发现股份有限公司 | 2024-07-16 | — | — | CN | disclosed |
| EP-0715618-A1 | HYDROXYETHYLAMINO SULPHONAMIDES USEFUL AS RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 1996-06-12 | — | — | EP | disclosed |
| WO-1995006030-A1 | HYDROXYETHYLAMINO SULPHONAMIDES USEFUL AS RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 1995-03-02 | — | — | WO | disclosed |
| EP-0296673-B1 | Thiazole derivatives | SHELL INT RESEARCH (NL) | 1994-03-09 | — | — | EP | disclosed |
| CN-1022015-C | Bactericidal composition containing thiazole derivative | SHELL INT RESEARCH (NL) | 1993-09-08 | — | — | CN | disclosed |
| US-4877802-A | FUNGICIDES | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 1989-10-31 | — | — | US | disclosed |
| CN-1033626-A | Thiazole derivative | SHELL INT RESEARCH (NL) | 1989-07-05 | — | — | CN | disclosed |
| EP-0296673-A1 | Thiazole derivatives | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1988-12-28 | — | — | EP | disclosed |