Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 1/20 | 0.49 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27599188 | 0.98 | CDC7 (0.48) | CDC7DBF4CYP2C9CYP2C19HPGD | |
| SCHEMBL27779004 | 0.83 | L3MBTL1 (0.50) | CYP2C9CYP2C19HSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL4832523 | 0.82 | ALDH1A1 (0.40) | CDC7DBF4CYP2C9CYP2C19HPGD | |
| SCHEMBL23293397 | 0.82 | KMT2A (0.40) | CDC7DBF4PKMALDH1A1MEN1 | |
| SCHEMBL28488682 | 0.80 | MGAM (0.44) | CYP2C19PKMKDM4EALDH1A1MEN1 | |
| SCHEMBL27641100 | 0.79 | KMT2A (0.36) | CDC7DBF4CYP2C9CYP2C19PKM | |
| SCHEMBL1726348 | 0.79 | — | — | |
| SCHEMBL8690008 | 0.78 | ALDH1A1 (0.36) | CDC7DBF4CYP2C9CYP2C19HPGD | |
| SCHEMBL4836930 | 0.77 | KMT2A (0.39) | CDC7DBF4CYP2C9CYP2C19HPGD | |
| SCHEMBL4836924 | 0.77 | KMT2A (0.39) | CDC7DBF4CYP2C9CYP2C19HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 413 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118666863-A | Pyrimidothienothiazole derivative or pharmaceutically acceptable salt thereof, and preparation and application thereof | 皖南医学院 | 2024-09-20 | — | — | CN | claimed |
| CN-110229117-A | A kind of novel preparation method of Febustat | 福安药业集团重庆博圣制药有限公司 | 2019-09-13 | — | — | CN | claimed |
| US-10224485-B2 | Process for preparing a crystalline organic semiconductor material | BASF SE (DE) | 2019-03-05 | — | — | US | claimed |
| CN-109354584-A | The method of one pot process 2- (4- hydroxy phenyl) -4- methyl-1,3-thiazole-5-carboxylic acid ethyl ester | 湖北理工学院 | 2019-02-19 | — | — | CN | claimed |
| CN-104220069-B | Trpm8 antagonists | 多姆皮制药公司 | 2018-10-02 | — | — | CN | claimed |
| CN-107922374-A | New catechol derivatives and the pharmaceutical composition containing it | 自体吞噬科学有限公司 | 2018-04-17 | — | — | CN | claimed |
| CN-107849040-A | tricyclic derivative compound, preparation method thereof, and pharmaceutical composition containing the same | 第药品株式会社 | 2018-03-27 | — | — | CN | claimed |
| CN-105777664-B | Carboxylate of 2 (2 benzyl hydrazono-) thiazole 5 and preparation method thereof and medical usage | 湖南大学 | 2017-12-29 | — | — | CN | claimed |
| CN-106632134-A | 2-(4-thiazolinone-2-imino)thiazole-5-carboxylate and preparation method and application thereof | 湖南大学 | 2017-05-10 | — | — | CN | claimed |
| US-20170012208-A1 | ORGANIC SEMICONDUCTOR FORMULATIONS | USINVEST LLC | 2017-01-12 | — | — | US | claimed |
| CN-101921243-B | Method for preparing 2-(3-formacyl-4-isobutoxyphenyl)-4-methyl-1,3 thiazole-5-carboxylic acid ethyl ester | QINGDAO HUANGHAI PHARMACEUTICAL CO LTD | 2012-10-10 | — | — | CN | claimed |
| CN-102239160-A | Substituted (pyridyl) -azinylamine derivatives as fungicides | BAYER CROPSCIENCE SA | 2011-11-09 | — | — | CN | claimed |
| CN-101921243-A | Method for preparing 2-(3-formacyl-4-isobutoxyphenyl)-4-methyl-1,3 thiazole-5-carboxylic acid ethyl ester | QINGDAO HUANGHAI PHARMACEUTICAL CO LTD | 2010-12-22 | — | — | CN | claimed |
| CN-101391988-B | Method for preparing 2- (4-hydroxyphenyl) -4-methyl-1, 3-thiazole-5-carboxylic acid ethyl ester by one-pot method | NANJING UNIVERSITY OF TECHNOLOGY | 2010-09-08 | — | — | CN | claimed |
| CN-101391988-A | Method for preparing 2- (4-hydroxyphenyl) -4-methyl-1, 3-thiazole-5-carboxylic acid ethyl ester by one-pot method | NANJING UNIVERSITY OF TECHNOLOGY (CN) | 2009-03-25 | — | — | CN | claimed |
| CN-101171250-A | Tricyclic derivatives of azetidine and pyrrole having antibacterial activity | ASTRAZENECA AB (SE) | 2008-04-30 | — | — | CN | claimed |
| CN-1729177-A | Novel uracils having herbicidal activity | ISAGRO RICERCA SRL (IT) | 2006-02-01 | — | — | CN | claimed |
| US-20260060970-A1 | Use of a Therapeutic Agent with Phosphodiesterase-7 Inhibitory Activity for the Treatment and Prevention of Diseases Associated with Chronic Fatigue, Exhaustion and/or Exertional Intolerance | MITODICURE GMBH (DE) | 2026-03-05 | — | — | US | disclosed |
| CN-87102123-A | Sulfonylurea compounds, their preparation and their use as herbicides | — | 1987-10-21 | — | — | CN | disclosed |
| EP-0192060-A1 | Heterocyclic compounds | NIHON BAYER AGROCHEM K.K. (JP) | 1986-08-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260060970-A1 | Use of a Therapeutic Agent with Phosphodiesterase-7 Inhibitory Activity for the Treatment and Prevention of Diseases Associated with Chronic Fatigue, Exhaustion and/or Exertional Intolerance | PDE5A, PDE4C, PDE12 | CDC7 214/4885DBF4 2228/4885CYP2C9 2510/4885 |
| US-10224485-B2 | Process for preparing a crystalline organic semiconductor material | STOM, SPOP, TTR | CDC7 826/4885DBF4 208/4885CYP2C9 764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.