Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 11/20 | 0.46 |
| ▸ | TERT | O14746 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KLK1 | P06870 | 1/20 | 0.38 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.38 |
| ▸ | TXN | P10599 | 1/20 | 0.38 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13995727 | 0.86 | TAAR1 (0.44) | TAAR1TERTALOX15KLK1KLK5 | |
| SCHEMBL25769704 | 0.82 | TERT (0.53) | TAAR1TERTALOX15TXNTXNRD1 | |
| SCHEMBL2474802 | 0.82 | TAAR1 (0.57) | TAAR1TERTALOX15KLK1KLK5 | |
| SCHEMBL10448528 | 0.81 | TAAR1 (0.42) | TAAR1TERTALOX15KLK1KLK5 | |
| SCHEMBL1040322 | 0.79 | — | — | |
| SCHEMBL369710 | 0.78 | TAAR1 (0.53) | TAAR1TERTALOX15KLK1KLK5 | |
| SCHEMBL6222239 | 0.77 | TAAR1 (0.49) | TAAR1TERTALOX15KLK1KLK5 | |
| SCHEMBL5355358 | 0.76 | TAAR1 (0.52) | TAAR1TERTALOX15KLK1KLK5 | |
| SCHEMBL6225559 | 0.76 | TAAR1 (0.47) | TAAR1TERTALOX15KLK1KLK5 | |
| SCHEMBL13995791 | 0.75 | TAAR1 (0.44) | TAAR1TERTALOX15KLK1KLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016105448-A1 | IMIDAZOLINE RECEPTOR TYPE 1 LIGANDS FOR USE AS THERAPEUTICS | RIDEOUT DARRYL (US) | 2016-06-30 | — | — | WO | disclosed |
| EP-1255738-B1 | GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO | NEUROCRINE BIOSCIENCES INC (US) | 2012-03-07 | — | — | EP | disclosed |