SCHEMBL2474802

SCHEMBL2474802

c1c[nH]c(CNCc2ncc[nH]2)n1

nearest known ligand 0.57

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 8/20 0.57
TERT O14746 1/20 0.48
ALOX15 P16050 1/20 0.48
KLK1 P06870 1/20 0.45
KLK5 Q9Y337 1/20 0.45
FPR2 P25090 1/20 0.44
FDPS P14324 1/20 0.41
TBXAS1 P24557 2/20 0.40
HTR1A P08908 1/20 0.40
ALDH1A1 P00352 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL369710 0.91 TAAR1 (0.53) TAAR1TERTALOX15KLK1KLK5
SCHEMBL5355358 0.89 TAAR1 (0.52) TAAR1TERTALOX15KLK1KLK5
SCHEMBL1040322 0.87
SCHEMBL4775864 0.85 TERT (0.59) TAAR1TERTALOX15KLK1KLK5
SCHEMBL2475485 0.84 TAAR1 (0.62) TAAR1ALDH1A1SMN1; SMN2
SCHEMBL4985592 0.83 TAAR1 (0.47) TAAR1TERTALOX15KLK1KLK5
SCHEMBL1971764 0.83 TAAR1 (0.47) TAAR1TERTALOX15KLK1KLK5
SCHEMBL6225559 0.83 TAAR1 (0.47) TAAR1TERTALOX15KLK1KLK5
SCHEMBL7748015 0.82 TAAR1 (0.46) TAAR1TERTALOX15KLK1KLK5
Ammonia Solution, Strong SCHEMBL28870904 0.82 TAAR1 (0.46) TAAR1TERTALOX15KLK1KLK5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150110716-A1 METHODS OF USING SPECT/CT ANALYSIS FOR STAGING CANCER MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) 2015-04-23 US claimed
US-20100098633-A1 SELECTIVE SEPRASE INHIBITORS MOLECULAR INSIGHT PHARMACEUTICALS, INC. 2010-04-22 US claimed
US-5708022-A RUTHENIUM COMPLEXES PROCEPT, INC. (US) 1998-01-13 US claimed
WO-1996013510-A1 RUTHENIUM COMPLEXES AND THEIR USE AS IMMUNOSUPPRESSIVE AGENTS PROCEPT, INC. (US) 1996-05-09 WO claimed
US-20240327549-A1 METAL-CONTAINING POLYMERS FOR MASS CYTOMETRY STANDARD BIOTOOLS CANADA INC. (CA) 2024-10-03 US disclosed
EP-4367164-A1 METAL-CONTAINING POLYMERS FOR MASS CYTOMETRY The Governing Council of the University of Toronto (CA) 2024-05-15 EP disclosed
CN-117820098-A Method for preparing linear aldehyde by olefin selective hydroformylation 复旦大学 2024-04-05 CN disclosed
CN-117813339-A Metal-containing polymers for mass flow cytometry 多伦多大学理事会 2024-04-02 CN disclosed
WO-2023279211-A1 METAL-CONTAINING POLYMERS FOR MASS CYTOMETRY THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) 2023-01-12 WO disclosed
US-10184052-B2 Near infrared radiation-absorbing composition, near infrared radiation cut-off filter and production method therefor, and camera module and production method therefor FUJIFILM CORPORATION (JP) 2019-01-22 US disclosed
US-20180094086-A1 NEAR INFRARED ABSORBING COMPOSITION, NEAR INFRARED CUT FILTER, METHOD OF MANUFACTURING NEAR INFRARED CUT FILTER, DEVICE, METHOD OF MANUFACTURING COPPER-CONTAINING POLYMER, AND COPPER-CONTAINING POLYMER FUJIFILM CORPORATION (JP) 2018-04-05 US disclosed
US-20170227690-A1 NEAR INFRARED RAY ABSORBENT COMPOSITION, NEAR INFRARED RAY CUT FILTER, SOLID IMAGE PICKUP ELEMENT, AND CAMERA MODULE FUJIFILM CORPORATION (JP) 2017-08-10 US disclosed
US-5512687-A RUTHENIUM COMPLEXES PROCEPT, INC. (US) 1996-04-30 US disclosed
WO-1996006157-A1 DETERGENT BLEACH COMPOSITION UNILEVER N.V. (NL) 1996-02-29 WO disclosed
WO-1996006154-A1 DETERGENT BLEACH COMPOSITION UNILEVER N.V. (NL) 1996-02-29 WO disclosed
US-5274147-A Reacting a manganese(III) salt with a ligand and oxidizing the complex with hydrogen peroxide LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1993-12-28 US disclosed
US-5244594-A BLEACH ACTIVATION MULTINUCLEAR MANGANESE-BASED COORDINATION COMPLEXES LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1993-09-14 US disclosed
EP-0544490-A1 Detergent bleach compositions UNILEVER PLC (GB) 1993-06-02 EP disclosed
EP-0522817-A1 Process for preparing manganese complexes UNILEVER PLC (GB) 1993-01-13 EP disclosed
EP-0458398-A2 Bleach activation UNILEVER N.V. (NL) 1991-11-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100098633-A1 SELECTIVE SEPRASE INHIBITORS SLC6A7, DNPEP, PREP TAAR1 1716/4885TERT 4403/4885ALOX15 4302/4885
US-20150110716-A1 METHODS OF USING SPECT/CT ANALYSIS FOR STAGING CANCER KLK3, SHBG, FOLH1 TAAR1 1861/4885TERT 3314/4885ALOX15 4759/4885
US-20170227690-A1 NEAR INFRARED RAY ABSORBENT COMPOSITION, NEAR INFRARED RAY CUT FILTER, SOLID IMAGE PICKUP ELEMENT, AND CAMERA MODULE C9, SET, CRY1 TAAR1 3067/4885TERT 2680/4885ALOX15 2928/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.