SCHEMBL17264167

SCHEMBL17264167

CONc1cccc(O)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.54
TSHR P16473 1/20 0.54
ALDH1A1 P00352 5/20 0.53
CYP1A2 P05177 3/20 0.53
RAPGEF4 Q8WZA2 1/20 0.50
KMT2A Q03164 6/20 0.48
HDAC6 Q9UBN7 1/20 0.48
HSD17B10 Q99714 3/20 0.48
CA12 O43570 1/20 0.48
CA2 P00918 1/20 0.48
LMNA P02545 1/20 0.48
CA5A P35218 1/20 0.48
CA9 Q16790 1/20 0.48
CA14 Q9ULX7 1/20 0.48
CA5B Q9Y2D0 1/20 0.48
MEN1 O00255 4/20 0.46
MAPT P10636 4/20 0.46
MAPK1 P28482 2/20 0.46
USP2 O75604 1/20 0.46
APP P05067 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11639364 0.85 MEN1 (0.42) TSHRALDH1A1KMT2AMEN1MAPT
SCHEMBL27485342 0.79 ALDH1A1 (0.47) CYP3A4TSHRALDH1A1CYP1A2RAPGEF4
SCHEMBL4716631 0.78 ALDH1A1 (0.59) CYP3A4TSHRALDH1A1CYP1A2RAPGEF4
SCHEMBL10448028 0.77 MAPT (0.54) CYP3A4ALDH1A1CYP1A2KMT2AHSD17B10
SCHEMBL54893 0.76
SCHEMBL29807871 0.76
SCHEMBL1187729 0.76 GAA (0.50) ALDH1A1RAPGEF4KMT2ALMNACA14
SCHEMBL6310754 0.76 ALDH1A1 (0.55) CYP3A4ALDH1A1RAPGEF4KMT2AHDAC6
SCHEMBL12344972 0.76 MEN1 (0.50) TSHRALDH1A1RAPGEF4KMT2ACA12
SCHEMBL15656150 0.76 SIGMAR1 (0.43) CA12CA2CA9APPGRIN2D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2756024-B1 LINEAR (PER)FLUOROPOLYETHERS WITH -CF(CF3)COF END GROUPS AND DERIVATIVES THEREOF SOLVAY SPECIALTY POLYMERS IT (IT) 2015-11-18 EP disclosed
CN-1024011-C Process for producing cephalosporin compound TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1994-03-16 CN disclosed
CN-1021226-C PREPARATION FOR ACYL DERIVATIVES HOFFMANN LA ROCHE (CH) 1993-06-16 CN disclosed
CN-87105204-A ACYL DERIVATIVES 1988-06-29 CN disclosed
CN-87101581-A Process for producing cephalosporin compound 1987-09-30 CN disclosed