Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 9/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | HNF4A | P41235 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13412638 | 0.94 | RXRA (0.43) | RXRAPPARGNR1H3HNF4ANR5A1 | |
| SCHEMBL12758295 | 0.90 | RXRA (0.41) | RXRAPPARGNR1H3LMNATP53 | |
| SCHEMBL3370746 | 0.89 | RXRA (0.41) | RXRAPPARGNR1H3HNF4A | |
| SCHEMBL4463620 | 0.84 | RXRA (0.43) | RXRAPPARGNR1H3HNF4AESR1 | |
| SCHEMBL4461726 | 0.84 | RXRA (0.43) | RXRAPPARGNR1H3HNF4AESR1 | |
| SCHEMBL4460088 | 0.84 | RXRA (0.43) | RXRAPPARGNR1H3HNF4AESR1 | |
| SCHEMBL81753 | 0.83 | RXRA (0.41) | RXRAPPARGNR1H3HNF4ATP53 | |
| SCHEMBL4464590 | 0.80 | RXRA (0.41) | RXRAPPARGNR1H3HNF4AESR1 | |
| SCHEMBL4474023 | 0.79 | RXRA (0.41) | RXRAPPARGNR1H3HNF4AESR1 | |
| SCHEMBL15867100 | 0.77 | ESR1 (0.34) | RXRAPPARGNR1H3HNF4AESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150330602-A1 | WAVE LENGTH CONVERSION MEMBER, BACK LIGHT UNIT, LIQUID CRYSTAL DISPLAY DEVICE, AND QUANTUM DOT-CONTAINING POLYMERIZABLE COMPOSITION | FUJIFILM CORPORATION (JP) | 2015-11-19 | — | — | US | disclosed |