SCHEMBL4474023

SCHEMBL4474023

CCCCOc1cc2c(cc1O)C1(CC2(C)C)CC(C)(C)c2cc(OCCCC)c(O)cc21

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
RXRA P19793 11/20 0.41
PPARG P37231 1/20 0.37
NR1H3 Q13133 1/20 0.37
ESR1 P03372 2/20 0.36
HNF4A P41235 2/20 0.36
SMPD1 P17405 1/20 0.35
DRD3 P35462 4/20 0.35
DRD1 P21728 3/20 0.35
DRD2 P14416 2/20 0.35
RARA P10276 1/20 0.33
RARB P10826 1/20 0.33
RARG P13631 1/20 0.33
RXRB P28702 1/20 0.33
RXRG P48443 1/20 0.33
ESR2 Q92731 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4460088 0.96 RXRA (0.43) RXRAPPARGNR1H3ESR1HNF4A
SCHEMBL4463620 0.96 RXRA (0.43) RXRAPPARGNR1H3ESR1HNF4A
SCHEMBL4461726 0.96 RXRA (0.43) RXRAPPARGNR1H3ESR1HNF4A
SCHEMBL4469326 0.94 RXRA (0.38) RXRAPPARGNR1H3ESR1HNF4A
SCHEMBL4460159 0.93 RXRA (0.38) RXRAPPARGNR1H3ESR1HNF4A
SCHEMBL4464590 0.91 RXRA (0.41) RXRAPPARGNR1H3ESR1HNF4A
SCHEMBL4464095 0.90 RXRA (0.33) RXRA
SCHEMBL3370746 0.89 RXRA (0.41) RXRAPPARGNR1H3HNF4ARARA
SCHEMBL4474777 0.89 APP (0.36) RXRAPPARGNR1H3HNF4ADRD3
SCHEMBL4466037 0.88 OPRM1 (0.37) RXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7582355-B2 Optical unit using plastic lenses FUJIFILM CORPORATION (JP) 2009-09-01 US disclosed
US-20060046065-A1 Optical unit using plastic lenses FUJI PHOTO FILM CO., LTD. 2006-03-02 US disclosed
US-6028161-A EXCELLENT TRANSPARENCY, HEAT RESISTANCE AND MECHANICAL PROPERTIES AND A LOW BIREFRINGENCE, MELT FLUIDITY AND MOLDABILITY; AN OPTICAL DISK, LENS AND AN OPTICAL FIBER MITSUI CHEMICALS, INC. (JP) 2000-02-22 US disclosed
EP-0926180-A2 A polycarbonate copolymer and applications thereof Mitsui Chemicals, Inc. (JP) 1999-06-30 EP disclosed