Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 6/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MYC | P01106 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1219970 | 0.79 | KMT2A (0.58) | HSP90AA1HSP90AB1ALDH1A1MEN1KMT2A | |
| SCHEMBL1746274 | 0.76 | ALDH1A1 (0.41) | HSP90AA1HSP90AB1MAPK14ALDH1A1POLB | |
| SCHEMBL1746273 | 0.76 | ALDH1A1 (0.41) | HSP90AA1HSP90AB1MAPK14ALDH1A1POLB | |
| SCHEMBL1746111 | 0.75 | HSP90AA1 (0.42) | HSP90AA1HSP90AB1MAPK14ALDH1A1POLB | |
| SCHEMBL1746115 | 0.75 | HSP90AA1 (0.42) | HSP90AA1HSP90AB1MAPK14ALDH1A1POLB | |
| SCHEMBL1220730 | 0.70 | KMT2A (0.55) | HSP90AA1HSP90AB1ALDH1A1MEN1KMT2A | |
| SCHEMBL1220639 | 0.68 | KMT2A (0.56) | HSP90AA1HSP90AB1ALDH1A1MEN1KMT2A | |
| SCHEMBL1220269 | 0.67 | KMT2A (0.51) | HSP90AA1HSP90AB1ALDH1A1MEN1KMT2A | |
| SCHEMBL1220323 | 0.66 | HSP90AA1 (0.52) | HSP90AA1HSP90AB1ALDH1A1MEN1KMT2A | |
| SCHEMBL1221436 | 0.66 | KMT2A (0.47) | HSP90AA1HSP90AB1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150329493-A1 | OMEGA-AMINO ACID DERIVATIVES OF BENZENE, PYRIDINE, AND PYRIDAZINE COMPOUNDS | HALL STEVEN E (US) | 2015-11-19 | — | — | US | disclosed |
| US-20150329493-A1 | OMEGA-AMINO ACID DERIVATIVES OF BENZENE, PYRIDINE, AND PYRIDAZINE COMPOUNDS | HALL STEVEN E (US) | 2015-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150329493-A1 | OMEGA-AMINO ACID DERIVATIVES OF BENZENE, PYRIDINE, AND PYRIDAZINE COMPOUNDS | LTB4R, LTB4R2, PTGER4 | HSP90AA1 3559/4885HSP90AB1 3629/4885MAPK14 2079/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.